During the many idle moments that comprise daily life, the human brain increases its activity across a set of midline and lateral cortical brain regions known as the “default network.” Despite the robustness with which the brain defaults to this pattern of activity, surprisingly little is known about the network’s precise anatomical organization and adaptive functions. To provide insight into these questions, this article synthesizes recent literature from structural and functional imaging with a growing behavioral literature on mind wandering. Results characterize the default network as a set of interacting hubs and subsystems that play an important role in “internal mentation”—the introspective and adaptive mental activities in which humans spontaneously and deliberately engage in every day.
AbrahamASchubotzRIvon CramonDY. 2008. Thinking about the future versus the past in personal and non-personal contexts. Brain Res1233:106–19.
2.
AddisDRPanLVuM-ALaiserNSchacterDL. 2009. Constructive episodic simulation of the future and the past: distinct subsystems of a core brain network mediate imagining and remembering. Neuropsychologia47:2222–38.
3.
AddisDRWongATSchacterDL. 2007. Remembering the past and imagining the future: common and distinct neural substrates during event construction and elaboration. Neuropsychologia45(7):1363–77.
4.
AmodioDFrithC. 2006. Meeting of minds: the medial frontal cortex and social cognition. Nat Rev Neurosci7:268–77.
5.
AndreasenNCO’LearyDSCizadlloTArndtSRezaiKWatkinsG, and others. 1995. Remembering the past: two facets of episodic memory explored with positron emission tomography. J Am Psychiatry152:1576–85.
6.
Andrews-HannaJRReidlerJSHuangCBucknerR. 2010. Evidence for the default network’s role in spontaneous cognition. J Neurophysiol104:322–35.
7.
Andrews-HannaJRReidlerJSSepulcreJPoulinRBucknerR. 2010. Functional-anatomic fractionation of the brain’s default network. Neuron65(4):550–62.
8.
Andrews-HannaJRSnyderAZVincentJLLustigCHeadDRaichleME, and others. 2007. Disruption of large-scale brain systems in advanced aging. Neuron56(5):924–35.
9.
AntrobusJSSingerJLGreenbergS. 1966. Studies in the stream of consciousness: experimental enhancement and suppression of spontaneous cognitive processes. Percept Motor Skills23:399–417.
10.
AtlasLBolgerNLindquistKWagerT. 2010. Brain mediators of predictive cue effects on perceived pain. J Neurosci30:12964–77.
11.
BaarsB. 2010. Spontaneous repetitive thoughts can be adaptive: postscript on “mind wandering.”Psychol Bull136: 208–10.
12.
BallardKKnustonB. 2009. Dissociable neural representations of future reward magnitude and delay during temporal discounting. Neuroimage45:143–50.
13.
BarM. 2007. The proactive brain: using analogies and associations to generate predictions. Trends Cogn Sci11:280–9.
14.
BarbasHGhashghaeiHDombrowskiSRempel-ClowerN. 1999. Medial prefrontal cortices are unified by common connections with superior temporal cortices and distinguished by input from memory-related areas in the rhesus monkey. J Comp Neurol410:343–67.
15.
BartelsAZekiS. 2004. The neural correlates of maternal and romantic love. Neuroimage21:1155–66.
16.
BenoitRGilbertSVolleEBurgessP. 2010. When I think about me and simulate you: medial rostral prefrontal cortex and self-referential processes. Neuroimage50:1340–9.
17.
BinderJRDesaiRGravesWConantL. 2009. Where is the semantic system? A critical review and meta-analysis of 120 functional neuroimaging studies. Cereb Cortex19:2767–96.
18.
BinderJRFrostJAHammekeTABellgowanPSRaoSMCoxRW. 1999. Conceptual processing during the conscious resting state: a functional MRI study. J Cogn Neurosci11:80–95.
19.
BresslerSMenonV. 2010. Large-scale brain networks in cognition: emerging methods and principles. Trends Cogn Sci14(6):277–90.
20.
BroydSBemanueleCDebenerSHelpsSJamesCSonuga-BarkeS, and others. 2009. Default-mode brain dysfunction in mental disorders: a systematic review. Neurosci Biobehav Rev33(3):279–96.
21.
BucknerRL. 2010. The role of the hippocampus in prediction and imagination. Annu Rev Psychol61:27–48.
22.
BucknerRLAndrews-HannaJRSchacterDL. 2008. The brain’s default network: anatomy, function and relevance to disease. Ann N Y Acad Sci1124:1–38.
23.
BucknerRLCarrollDC. 2007. Self-projection and the brain. Trends Cogn Sci11:49–57.
24.
BucknerRLSepulcreJTalukdarTKrienenFMLiuHHeddenT, and others. 2009. Cortical hubs revealed by intrinsic functional connectivity: mapping, assessment of stability, and relation to Alzheimer’s disease. J Neurosci29:1860–73.
25.
BucknerRLSnyderAZShannonBJLaRossaGSachsRFotenosA, and others. 2005. Molecular, structural, and functional characterization of Alzheimer’s disease: evidence for a relationship between default activity, amyloid, and memory. J Neurosci25:7709–17.
CavadaCGoldman-RakicP. 1989. Posterior parietal cortex in rhesus monkey, I: parcellation of areas based on distinctive limbic and sensory corticocortical connections. J Comp Neurol287:393–421.
28.
ChibVRangelAShimojoSO’DohertyJ. 2009. Evidence for a common representation of decision values for dissimilar goods in human ventromedial prefrontal cortex. J Neurosci29:12315–20.
29.
ChristoffKGordonASmallwoodJSmithRSchoolerJ. 2009. Experience sampling during fMRI reveals default network and executive system contributions to mind wandering. Proc Natl Acad Sci U S A106:8719–24.
30.
ChristoffKGordonASmithR. 2008. The role of spontaneous thought in human cognition. In: VartanianO.MandelD., editors. Neuroscience of decision making. New York (NY): Psychology Press, p. 259-84.
31.
D’ArgembeauAStawarczykDMajerusSColletteFVan der LindenMFeyersD, and others. 2010. The neural basis of personal goal processing when envisioning future events. J Cogn Neurosci22(8):1701–3.
32.
DamoiseauxJSBeckmannCFArigitaEBarkhofFScheltensPStamCJ, and others. 2008. Reduced resting-state brain activity in the “default network” in normal aging. Cereb Cortex18(8):1856–4.
33.
DaselaarSMPrinceSEDennisNAHayesSMKimHCabezaR. 2009. Posterior midline and ventral parietal activity is associated with retrieval success and encoding failure. Front Hum Neurosci3:13.
34.
DaselaarSMPoratYHuijbersWPennartzC. 2010. Modality-specific and modality-independent components of the human imagery system. Neuroimage52:677–85.
35.
DelamillieurePDoucetGMazoyerPTurbelinM-RDelcroixNMelletE, and others. 2010. The resting state questionnaire: an introspective questionnaire for evaluation of inner experience during the conscious resting state. Brain Res Bull81:565–73.
36.
Dodell-FederDKoster-HaleJBednyMSaxeR. 2011. fMRI item analysis in a theory of mind task. Neuroimage55(2): 705-12.
37.
DomhoffGW. Forthcoming. The neural substrate for dreaming: is it a subsystem of the default network?Conscious Cogn.
38.
Ersner-HershfieldHWimmerE. GKnutsonB. 2008. Saving for the future self: neural measures of future self-continuity predict temporal discounting. Soc Cogn Affect Neurosci4: 85–92.
39.
FoxMDRaichleME. 2007. Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging. Nat Rev Neurosci8:700–11.
40.
FoxMDSnyderAZVincentJLCorbettaMVan EssenDCRaichleME. 2005. The human is intrinsically organized into dynamic, anticorrelated functional networks. Proc Natl Acad Sci U S A102:9673–8.
41.
FranssonPMarrelecG. 2008. The precuneus/posterior cingulate plays a pivotal role in the default mode network: evidence from partial correlation analysis. Neuroimage42(3):1178–84.
42.
FrithUFrithC. 2003. Development and neurophysiology of mentalizing. Phil Transact R Soc Lond358:459–73.
43.
GerlachKSprengRNGilmoreASchacterDL. 2011. Solving future problems: default network and executive activity associated with goal-directed mental simulations. Neuroimage55(4):1816-24.
44.
GilbertDWilsonT. 2007. Prospection: experiencing the future. Science317:1351–4.
45.
GilbertSJDumontheilISimonsJSFrithCDBurgessPW. 2007. Comment on “Wandering minds: the default network and stimulus-independent thought.”Science317:43.
46.
GilbertSJFrithCDBurgessPW. 2005. Involvement of rostral prefrontal cortex in selection between stimulus-oriented and stimulus-independent thought. Eur J Neurosci21(5):1423–31.
47.
GilbertSJSimonsJSFrithCDBurgessPW. 2006. Performance-related activity in medial rostral prefrontal cortex (area 10) during low-demand tasks. J Exp Psychol Hum Percept Perform32:45–58.
48.
GollandYGollandPBentinSMalachR. 2008. Data-driven clustering reveals a fundamental subdivision of the human cortex into two global systems. Neuropsychologia46:540–53.
GreiciusMDSupekarKMenonVDoughertyR. 2009. Resting state functional connectivity reflects structural connectivity in the default mode network. Cereb Cortex19:72–8.
51.
GreiciusMDKrasnowBReissALMenonV. 2003. Functional connectivity in the resting brain: a network analysis of the default mode hypothesis. Proc Natl Acad Sci U S A100:253–8.
52.
GreiciusMDSrivastavaGReissALMenonV. 2004. Default-mode network activity distinguishes Alzheimer’s disease from healthy aging: evidence from functional MRI. Proc Natl Acad Sci U S A101:4637–42.
53.
GriggOGradyCL. 2010. The default network and processing of personally relevant information: converging evidence from task-related modulations and functional connectivity. Neuropsychologia48(13):3815–23.
54.
GusnardDRaichleME. 2001. Searching for a baseline: functional imaging and the resting human brain. Nat Rev Neurosci2:685–94.
55.
HagmannPCammounLGiagandetXMeuliRHoneyCWedeenV, and others. 2008. Mapping the structural core of human cerebral cortex. PLoS One6:1479–93.
56.
HahnBRossTJSteinEA. 2007. Cingulate activation increases dynamically with response speed under stimulus unpredictability. Cereb Cortex17:1664–71.
57.
HareTACamererCRangelA. 2009. Self-control in decision-making involves modulation of the vMPFC valuation system. Science324:646–8.
58.
HassabisDKumaranDMaguireEA. 2007. Using imagination to understand the neural basis of episodic memory. J Neurosci27:14365–74.
59.
HassabisDMaguireEA. 2007. Deconstructing episodic memory with construction. Trends Cogn Sci11(7):299–306.
60.
HillJInderTNeilJDierkerDHarwellJVan EssenD. 2010. Similar patterns of cortical expansion during human development and evolution. Proc Natl Acad Sci U S A107(29):13135–40.
61.
IngvarD. 1979. “Hyperfrontal” distribution of the cerebral grey matter flow in resting wakefulness: on the functional anatomy of the conscious state. Acta Neurol Scand60:12–25.
62.
JenkinsACMitchellJP. 2010. Medial prefrontal cortex subserves diverse forms of self-reflection. Soc Neurosci12:1–8.
63.
JohnsonSSchmitzTKawahara-BaccusTRowleyHAlexanderALeeJ, and others. 2005. The cerebral response during subjective choice with and without self-reference. J Cogn Neurosci17:1897–906.
64.
KableJGlimcherP. 2007. The neural correlates of subjective value during intertemporal choice. Nat Neurosci10:1625–33.
65.
KillingsworthMGilbertD. 2010. A wandering mind is an unhappy mind. Science330:932.
66.
KimHDaselaarSMCabezaR. 2010. Overlapping brain activity between episodic memory encoding and retrieval: roles of the task-positive and task-negative networks. Neuroimage49:1045–54.
67.
KlingerE. 1971. Structure and functions of fantasy. New York (NY): John Wiley.
68.
KlingerECoxW. 1987. Dimensions of thought flow in everyday life. Imag Cogn Person7:105–28.
69.
KlingerE. 2009. Daydreaming and fantasizing: thought flow and motivation. In: MarkmanKDWMPKleinSuhrJA, editors. Handbook of imagination and mental simulation. New York (NY): Psychology Press, p. 225-240.
KoberHBarretLJosephJBliss-MoreauELindquistKWagerT. 2008. Functional grouping and cortical–subcortical interactions in emotion: a meta-analysis of neuroimaging studies. Neuroimage42:998–1031.
72.
KojimaTOnoeHHikosakaKTsutsuiKTsukadaHWatanabeK. 2009. Default mode of brain activity demonstrated by positron emission tomography imaging in awake monkeys: higher rest-related than working memory-related activity in medial cortical areas. J Neurosci29(46):14463–71.
73.
KrienenFTuPBucknerRL. 2010. Clan mentality: evidence that the medial prefrontal cortex responds to close others. J Neurosci30:13906–15.
74.
LairdAEickhoffSLiKRobinDGlahnDFoxP. 2009. Investigating the functional heterogeneity of the default mode network using coordinate-based meta-analytic modeling. J Neurosci29:14496–505.
75.
LiebermanM. 2007. Social cognitive neuroscience: a review of core processes. Annu Rev Psychol58:259–89.
76.
LombardoMChakrabartiBBullmoreEWheelwrightSSadekSSucklingJ, and others. 2010. Shared neural circuits for mentalizing about the self and others. J Cogn Neurosci22:1623–35.
MaddockR. 1999. The retrosplenial cortex and emotion: new insights from functional neuroimaging of the human brain. Trends Neurosci22:310–6.
79.
MakrisNPapadimitriouGKaiserJSorgSKennedyDPandyaD. 2009. Delineation of the middle longitudinal fascicle in humans: a quantitative, in vivo, DT-MRI study. Cereb Cortex19:777–85.
80.
MarguliesDVincentJLKelleyCLohmannGUddinLBiswalB, and others. 2009. Precuneus shares intrinsic functional architecture in humans and monkeys. Proc Natl Acad Sci U S A106:20069–74.
81.
MasonMFNortonMIVan HornJDWegnerDMGraftonSTMacraeCN. 2007. Wandering minds: the default network and stimulus-independent thought. Science215:393–5.
82.
MazoyerPZagoLMelletEBricogneSEtardOHoudéF, and others. 2001. Cortical networks for working memory and executive function sustain the conscious resting state in man. Brain Res Bull54:287–98.
83.
McClureSLaibsonDLoewensteinGCohenJ. 2004. Separate neural systems value immediate and delayed monetary rewards. Science306:503–7.
84.
McDermottKBSzpunarKKChristS. 2009. Laboratory-based and autobiographical retrieval tasks differ substantially in their neural substrates. Neuropsychologia47:2290–8.
85.
McKiernanKAD’AngeloBRKaufmanJNBinderJR. 2006. Interrupting the “stream of consciousness”: an fMRI investigation. Neuroimage29:1185–91.
86.
McVayJKaneM. 2010. Does mind wandering reflect executive function or executive failure? Comment on Smallwood and Schooler (2006) and Watkins (2008). Psychol Bull136:188–97.
87.
MenonVUddinLQ. 2010. Saliency, switching, attention and control: a network model of insula function. Brain Struct Funct214(5–6):655–67.
88.
MinoshimaSGiordaniBBerentSFreyKFosterNKuhlD. 1997. Metabolic reduction in the posterior cingulate cortex in very early Alzheimer’s disease. Ann Neurol42:85–94.
89.
MitchellJP. 2009. Inferences about mental states. Phil Transact R Soc Lond364:1309–16.
MollJZahnRde Oliveria-SouzaRKruegerFGrafmanJ. 2005. The neural basis of human moral cognition. Nat Rev Neurosci6(10):799–809.
92.
MontaguePKing-CasasBCohenJ. 2006. Imaging valuation models in human choice. Annu Rev Neurosci29:417–48.
93.
MoranJMHeathertonTFKelleyWM. 2009. Modulation of cortical midline structures by implicit and explicit self-relevance evaluation. Soc Neurosci4:197–211.
94.
MoranJMLeeSGabrieliJDE. Forthcoming. Dissociable neural systems supporting knowledge about human character and appearance in ourselves and others. J Cogn Neurosci.
95.
MoranJMMacraeCNHeathertonTFWylandCLKelleyWM. 2006. Neuroanatomical evidence for distinct cognitive and affective components of self. J Cogn Neurosci18:1586–94.
96.
MorcomAFletcherP. 2007. Does the brain have a baseline? Why we should be resisting a rest. Neuroimage37:1073–82.
97.
MorecraftRJCipolloniPBSitlwell-MorecrftKSGedneyMTPandyaDN. 2004. Cytoarchitecture and cortical connections of the posterior cingulate and adjacent somatosensory fields in the rhesus monkey. J Comp Neurol469:37–69.
98.
NirYTononiG. 2009. Dreaming and the brain: from phenomenology to neurophysiology Trends Cogn Sci14: 88–100.
99.
NorthoffGHeinzelAde GreckMBermpohlGDobrowolnyHPankseppJ. 2006. Self-referential processing in our brain—a meta-analysis of imaging studies on the self. Neuroimage31:440–57.
100.
OchsnerKBeerJRobertsonECooperJGabrieliJDEKihlstromJ, and others. 2005. The neural correlates of directed and reflected self-knowledge. Neuroimage28:797–814.
101.
OchsnerKKnierimKLudlowDHanelinJRamachandranTGloverG, and others. 2004. Reflecting upon feelings: an fMRI study of neural systems supporting the attribution of emotion to self and other. J Cogn Neurosci16:1746–72.
102.
OlssonAOchsnerK. 2008. The role of social cognition in emotion. Trends Cogn Sci12:65–71.
103.
OngürDFerryAPriceJL. 2003. Architectonic subdivision of the human orbital and medial prefrontal cortex. J Comp Neurol460:425–49.
104.
ParviziJVan HoesenGBuckwalterJDamasioA. 2006. Neural connections of the posteromedial cortex in the macaque. Proc Natl Acad Sci U S A103:1563–8.
105.
PetersJBüchelC. 2010. Episodic future thinking reduces reward delay discounting through an enhancement of prefrontal-mediotemporal interactions. Neuron66:138–48.
106.
PfefferbaumAChanraudSPitelA-LMüller-OehringEShankaranarayananAAlsopD, and others. 2011. Cerebral blood flow in posterior cortical nodes of the default mode network decreases with task engagement but remains higher than in most brain regions. Cereb Cortex21(1):233–44.
107.
PowerJFairDSchlaggarBPetersenS. 2010. The development of human functional brain networks. Neuron67:735–48.
108.
RaichleMEMacLeodAMSnyderAZPowersWJGusnardD, and others. 2001. A default mode of brain function. Proc Natl Acad Sci U S A98:676–82.
109.
RabinJSGilboaAStussDTMarRARosenbaumRS. 2010. Common and unique neural correlates of autobiographical memory and theory of mind. J Cogn Neurosci22(6):1095–111.
110.
RaichleMESnyderAZ. 2007. A default mode of brain function: a brief history of an evolving idea. Neuroimage37:1083–90.
111.
ReichleEReinebergASchoolerJ. 2010. Eye movements during mindless reading. Psychol Sci21:1300–10.
112.
RillingJKBarksSParrLPreussTFaberTPagnoniG, and others. 2007. A comparison of resting-state brain activity in humans and chimpanzees. Proc Natl Acad Sci U S A104:17146–51.
113.
RillingJKSanfeyAGAronsonJANystromLECohenJD. 2004. The neural correlates of theory of mind within interpersonal interactions. Neuroimage22:1694–703.
114.
SajonzBKahntTMarguliesDParkSWhittmannAStoyM, and others. 2010. Delineating self-referential processing from episodic memory retrieval: common and dissociable networks. Neuroimage50:1606–17.
115.
SchacterDLAddisDRBucknerRL. 2008. Episodic simulation of future events: concepts, data, and applications. Ann N Y Acad Sci1124:39–60.
116.
SchilbachLEickhoffSBRotarska-JagielaAFinkGRVogeleyK. 2008. Minds at rest? Social cognition as the default mode of cognizing and its putative relationship to the “default system” of the brain. Conscious Cogn17:457–67.
117.
SchmitzTJohnsonS. 2007. Relevance to self: a brief review and framework of neural systems underlying appraisal. Neurosci Biobehav Rev31:585–96.
118.
ScovilleWBMilnerB. 1957. Loss of recent memory after bilateral hippocampal lesions. J Neurol Neurosurg Psychol20:11–21.
119.
ShelineYIBarchDMPriceJLRundleMVaishnaviSSnyderAZ, and others. 2009. The default mode network and self-referential processes in depression. Proc Natl Acad Sci U S A106:1942–7.
120.
ShulmanGLFiezJACorbettaMBucknerRLMiezenFMRaichleME, and others. 1997. Common blood flow changes across visual tasks, II: decreases in cerebral cortex. J Cogn Neurosci9:648–63.
121.
SingerJL. Daydreaming: an introduction to the experimental study of inner experience. New York: Random House, Inc1966.
122.
SmallDGitelmanDGregoryMNobreAParrishTMesulamM-M. 2003. The posterior cingulate and medial prefrontal cortex mediate the anticipatory allocation of spatial attention. Neuroimage18:633–41.
123.
SmallwoodJ. 2010. Why the global availability of mind wandering necessitates resource competition: reply to McVay and Kane. Psychol Bull136(2): 202.
124.
SmallwoodJSchoolerJW. 2006. The restless mind. Psychol Bull132:946–58.
125.
SmallwoodJBrownKBairdBSchoolerJW. Forthcoming. Cooperation between the default mode network and the frontal-parietal network in the production of an internal train of thought. Brain Res.
126.
SmithSFoxPMillerKGlahnDFoxPMackayC, and others. 2009. Correspondence of the brain’s functional architecture during activation and rest. Proc Natl Acad Sci U S A106:13040–5.
127.
SperlingRLaviolettePO’KeefeKO’BrianJRentzDPihlajamakiM, and others. 2009. Amyloid deposition is associated with impaired default network function in older persons without dementia. Neuron63:178–88.
128.
SpiersHMaguireEA. 2006. Thoughts, behaviour, and brain dynamics during navigation in the real world. Neuroimage31:1826–40.
129.
SprengRNGradyCL. 2010. Patterns of brain activity supporting autobiographical memory, prospection, and theory of mind, and their relationship to the default mode network. J Cogn Neurosci22:1112–23.
130.
SprengRNMarRAKimAS. 2009. The common neural basis of autobiographical memory, prospection, navigation, theory of mind, and the default mode: a quantitative meta-analysis. J Cogn Neurosci21:489–510.
131.
SprengNRStevensWDChamberlainJPGilmoreAWSchacterDL. 2010. Default network activity, coupled with the frontoparietal control network, supports goal-directed cognition. Neuroimage53:303–17.
132.
St. JacquesPConwayMLowderMCabezaR. Forthcoming. Watching my mind unfold versus yours: an fMRI study using a novel camera technology to examine neural differences in self-projection of self versus other perspectives. J Cogn Neurosci.
133.
SummerfieldJJHassabisDMaguireEA. 2010. Differential engagement of brain regions within a “core” network during scene construction. Neuropsychologia48:1501–9.
134.
SummerfieldJJHassabisDMaguireEA. 2009. Cortical midline involvement in autobiographical memory. Neuroimage44:1188–200.
135.
SvobodaEMcKinnonMLevineB. 2006. The functional neuroanatomy of autobiographical memory: a meta-analysis. Neuropsychologia44:2189–208.
136.
Szpunar KK. 2010. Episodic future thought: an emerging concept. Perspect Psychol Sci5(2):142–62.
137.
SzpunarKKChanJCMcDermottKB. 2009. Contextual processing in episodic future thought. Cereb Cortex19:1539–48.
138.
SzpunarKKWatsonJMMcDermottKB. 2007. Neural substrates of envisioning the future. Proc Natl Acad Sci U S A104(2):642–7.
139.
TambiniAKetzNDavachiL. 2010. Enhanced brain correlations during rest are related to memory for recent experiences. Neuron65:280–90.
140.
TavaresPLawrenceABanardP. 2008. Paying attention to social meaning: an fMRI study. Cereb Cortex18:1876–85.
141.
TulvingE. 1985. How many memory systems are there?Am Psychol40:385–98.
142.
UddinLQSupekarKAminHRykhlevskaiaENguyenDGreiciusMD, and others. 2010. Dissociable connectivity within human angular gyrus and intraparietal sulcus: evidence from functional and structural connectivity. Cereb Cortex20:2636–46.
143.
van den HeuvelMMandlRKahnRPolH. 2009. Functionally linked resting-state networks reflect the underlying structural connectivity architecture of the human brain. Hum Brain Mapp30:3127–41.
144.
van der MeerLCostafredaSAlemanADavidA. 2010. Self-reflection and the brain: a theoretical review and meta-analysis of neuroimaging studies with implications for schizophrenia. Neurosci Biobehav Rev34:935–46.
145.
Van EssenDC. 2005. A population-average, landmark- and surface-based (PALS) atlas of human cerebral cortex. Neuroimage28:635–62.
146.
VanniniPO’BrienJO’KeefeKPihlajamäkiMLaviolettePSperlingRA. 2011. What goes down must come up: role of the posteromedial cortices in encoding and retrieval. Cereb Cortex21(1):22–34.
147.
Van OverwalleF. 2009. Social cognition and the brain: a meta-analysis. Hum Brain Map30:829–58.
148.
Van OverwalleF. 2011. A dissociation between social mentalizing and general reasoning. Neuroimage54:1589–99.
149.
VanhaudenhuyseADemertziASchabusMNoirhommeQBredartSBolyM, and others. 2010. Two distinct neuronal networks mediate the awareness of environment and of self. J Cogn Neurosci23:570–8.
150.
VannSAggletonJMaguireEA. 2009. What does the retrosplenial cortex do?Nat Rev Neurosci20:792–802.
151.
VincentJLKahnISnyderAZRaichleMEBucknerRL. 2008. Evidence for a frontoparietal control system revealed by intrinsic functional connectivity. J Neurophysiol100(6): 3328–42.
152.
VincentJLPatelGFoxMDSnyderAZBakerJVan EssenDC, and others. 2007. Intrinsic functional architecture in the anaesthetized monkey brain. Nature447:83–6.
153.
VincentJLSnyderAZFoxMDShannonBJAndrewsJRRaichleME, and others. 2006. Coherent spontaneous activity identifies a hippocampal-parietal memory network. J Neurophysiol96:3517–31.
154.
WagerTWaughCLindquistMNollDFredricksonBTaylorS. 2009. Brain mediators of cardiovascular responses to social threat, part I: reciprocal dorsal and ventral sub-regions of the medial prefrontal cortex and heart-rate reactivity. Neuroimage47:821–35.
155.
WamsleyEStickgoldR. 2010. Dreaming and offline memory processing. Curr Biol20:R1010.
156.
WangKYuCXuLQinWLiKXuL, and others. 2009. Offline memory reprocessing: involvement of the brain’s default network in spontaneous thought processes. PLoS One4:e4867.
157.
Whitfield-GabrieliSMoranJMNieto-CastanonATriantafyllouCSaxeRGabrieliJDE. 2011. Associations and dissociations between default and self-reference networks in the human brain. Neuroimage55:225–32.
158.
WigGGraftonSDemosKWolfordGPetersenSKelleyW. 2008. Medial temporal lobe bold activity at rest predicts individual differences in memory ability in healthy young adults. Proc Natl Acad Sci U S A105:18555–60.
159.
YarkoniTSpeerNZacksJ. 2008. Neural substrates of narrative comprehension and memory. Neuroimage41: 1408–25.
160.
ZhangDRaichleME. 2010. Disease and the brain’s dark energy. Nat Rev Neurol6:15–28.
