The management of cardiopulmonary bypass has evolved over the last 50 years resulting in a largely consistent approach to both adult and pediatric perfusion. Very little has been written or prospectively researched on the best practice for cardiopulmonary bypass in the high-risk elderly patient, despite the challenge this patient cohort presents compared to the general adult population and the rapidly increasing number of such patients undergoing cardiac surgery. We propose a framework for perfusion strategies for the high-risk elderly patient from our current understanding of cardiopulmonary bypass. It should stimulate discussion for a consensus on perfusion strategies for the elderly and encourage further research into perfusion variables as they relate to the outcome of patients of advanced age.
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