Acute 'upside-down' visual inversion due to multiple sclerosis

Abstract

In a 20-year-old male patient, a 180 degree inversion of visual image was found as a manifestation of multiple sclerosis. Upside down reversal of vision is not a well-known sign in multiple sclerosis. Exact mechanism is still unknown. Lesions involving cortical areas, mainly the parieto-occipital region, have occasionally been documented. To our knowledge this is the first report of upside-down reversal of vision in multiple sclerosis with cerebra lesion on MRI. Multiple Sclerosis 2008; 14: 266—267. http://msj.sagepub.com

Keywords

metamorphopsia multiple sclerosis reversal upside-down vision

Get full access to this article

View all access options for this article.

References

Solms M. , Kaplan-Solms K. , Saling M. , Miller P. Inverted vision after frontal lobe disease . Cortex 1988; 24: 499—509.

Mehler MF Complete visual inversion in vertebrobasilar ischaemic disease (letter) . J Neurol Neurosurg Psychiatry 1988; 55: 188—9.

Ropper AH Illusion of tilting of the visual environment . Report of five cases. J Clin Neurophtalmol 1983; 3: 147—51.

Steiner I. , Shahin R. , Melamed E. Acute `upside down' reversal of vision in transient vertebrobasilar ischemia . Neurology 1987; 37: 1685—6.

Charles N. , Froment C. , Rode G. et al. Vertigo and upside down vision due to an infarct in the territory of medial branch of the posterior inferior cerebellar artery caused by dissection of a vertebral artery . J Neurol Neurosurg Psychiatry 1992; 55: 188—9.

Pamir MN , Ozer AF , Siva A. , Ozek KK , Kansu T. `Upside-down reversal of vision' after third ventriculostomy . J Clin Neuro-ophthalmol 1990; 10: 2271—2.

Anderson RA , Essick GK , Siegel RM Encoding of spatial location by posterior parietal neurons . Science 1985; 230: 456—8.

Siegel AM Inverted vision in MS (letter) . Neurology 1988; 38: 1335 .

Dogŭlu CF , Kansu T. Upside-down reversal of vision in multiple sclerosis . J Neurol 1997; 244: 461—72.

10.

Hagström L. , Hörnsten G. , Silfverskiöld BP Oculostatic and visual phenomena occuring in association with Wallenberg's syndrome . Acta Neurol Scand 1969; 45: 568—2.