Recurrent natalizumab-related aseptic meningitis in a patient with multiple sclerosis

Abstract

Natalizumab is a recombinant humanized monoclonal antibody that decreases T-cell migration into the central nervous system (CNS) through α4 integrin:adhesion-molecule inhibition, thereby increasing the risk for opportunistic CNS infection. Herein, we report a case of infusion-associated aseptic meningitis in a patient receiving natalizumab.

Keywords

Multiple sclerosis natalizumab disease-modifying therapies MRI

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