Coupling structure and function in early MS: How a less diverse repertoire of brain function could lead to clinical progression

Chard D Alahmadi A Audoin B , et al. Mind the gap: From neurons to networks to outcomes in multiple sclerosis. Nature Rev Neur . Epub ahead of print 12 January 2021. DOI: 10.1038/s41582-020-00439-8.

Tewarie P Steenwijk MD Brookes MJ , et al. Explaining the heterogeneity of functional connectivity findings in multiple sclerosis: An empirically informed modeling study. Hum Brain Mapp 2018; 39(6): 2541–2548.

Koubiyr I Besson P Deloire M , et al. Dynamic modular-level alterations of structural-functional coupling in clinically isolated syndrome. Brain 2019; 142: 3428–3439.

Braun U Schäfer A Walter H , et al. Dynamic reconfiguration of frontal brain networks during executive cognition in humans. Proc Natl Acad Sci 2015; 112: 11678–11683.

Eijlers AJ Wink AM Meijer KA , et al. Reduced network dynamics on functional MRI signals cognitive impairment in multiple sclerosis. Radiology 2019; 292(2): 449–457.

Dai Z Lin Q Li T , et al. Disrupted structural and functional brain networks in Alzheimer’s disease. Neurobiol Aging 2019; 75: 71–82.

Koubiyr ID Deloire M Brochet B , et al. Structural constraints of functional connectivity drive cognitive impairment in the early stages of multiple sclerosis. Mult Scler 2021; 27(4): 559–567.

Muldoon SF Bassett DS. Network and multilayer network approaches to understanding human brain dynamics. Philos Sci 2016; 83: 710–720.

Rocca MA Hidalgo de La Cruz M Valsasina P , et al. Two-year dynamic functional network connectivity in clinically isolated syndrome. Mult Scler 2020; 26(6): 645–658.

Hidalgo de la Cruz M Valsasina P Mesaros S , et al. Clinical predictivity of thalamic sub-regional connectivity in clinically isolated syndrome: A 7-year study. Mol Psychiat. Epub ahead of print 22 April 2020. DOI: 10.1038/s41380-020-0726-4.