Abstract
Introduction
Treatment engagement, adherence, cancellations and other patient-centric data are important predictors of treatment outcome. But often these data are only examined retrospectively. In this investigation, we analysed data from a clinical trial focused on innovative delivery of depression treatment to identify which patients are likely to prefer either in-home or in-person treatment based on pre-treatment characteristics.
Methods
Patient satisfaction was assessed in a trial of individuals with depression treated using identical behavioural activation therapy protocols in person or through videoconferencing to the home (N = 87 at post treatment: 42 in-person and 45 in-home participants). The Client Satisfaction Questionnaire was administered at the end of the treatment. A Tobit regression model was used to assess moderation using treatment assignment. Regression lines were generated to model treatment satisfaction as a function of treatment assignment and to identify whether and where the groups intersected. We examined the distributions of the contributing moderators to the subsets of participants above and below the intersection point to identify differences.
Results
While no significant differences in patient satisfaction were observed between the two groups, or between patients receiving treatment by different providers, baseline characteristics of the sample could be used to differentiate those with a preference for traditional, in-office care from those preferring in-home care.
Discussion
Participants who were more likely to prefer in-home care were characterized by larger proportions of veterans and lower-ranked enlisted service members. They also had more severe symptoms at baseline and less formal education. Understanding client reactions when selecting treatment modality may allow for a more satisfying patient experience.
Introduction
Physicians and other health care providers often assess their patients’ participation – responsiveness to treatment; adherence to therapy; tardiness or cancellations; and other patient-centric information – as a part of standard health care practice. Patients’ satisfaction with received care should be an integral part of the health care process, ensuring a dynamic, responsive relationship between a patient and a provider. Mental health services are particularly affected by patient satisfaction, since therapeutic outcome largely depends on the quality of interactions between a provider and a patient, as well as the degree of therapeutic alliance.1–7 Ample evidence indicates that patients’ participation and satisfaction with the interaction, the treatment, and the provider are vital for a successful therapeutic relationship.8–10 It is, therefore, not surprising that attempts to measure patient satisfaction, starting in the early 1950s, involved mental health services.11–13
Patient satisfaction represents a complex outcome measure that combines a mixture of potential predisposing elements, including a patient’s characteristics, expectations, involvement and attitudes; the disease or illness itself and comorbid conditions; and provider-, environment- and therapeutic approach-associated factors.3,14–23 Among the factors that affect patient satisfaction is the presence of clinical depression. 14 Depression is associated with lower satisfaction with life, distorted views of others and self, and negative or destructive communication patterns with strangers, acquaintances and, particularly, with those closest to patients with depression.24–38 Lower levels of life satisfaction were observed in patients with major depressive disorder even during periods of diagnostic remission, 34 and there is a strong association between depression severity and life satisfaction. 24 Patients with depression may also experience difficulty interacting with others, problems with social skills, reduced motivation, and lower ability to cooperate to achieve a goal.35,39,40 These depression-related symptoms could impair patients’ ability to successfully engage in the treatment process, undermine their social support network and hinder their ability to constructively interact with health care providers. This can reduce the likelihood of a successful therapeutic outcome and, consequently, patient satisfaction in psychotherapy.
Patient satisfaction is further complicated in therapeutic modalities using telehealth options because attitudes towards technology, quality of the connection (e.g. audio and video quality) and other technology-based factors may contribute to or alter relevant elements responsible for patient’s satisfaction.41–46 While convenient access is often mentioned as a reason for high satisfaction among patients utilizing telehealth options for mental health,43,47–48 some patients may be best served by in-office treatment because of their individual clinical needs (e.g. loneliness, symptom severity, avoidance behaviour) and preferences (e.g. driving distance, work schedule, childcare needs).45,48–54 In addition to barriers to successful telemental health care associated with patients’ characteristics and attitudes, providers may also be resistant to, poorly prepared for or less capable of providing mental health care using telehealth options.55–56 Therefore, it is not surprising that some patients may not respond in the same way or receive the same benefit from services provided via telehealth or videoconferencing mental health care.54,57,58
Because treatment satisfaction is an important part of achieving a successful treatment outcome, we attempted to identify differential treatment satisfaction between two delivery modalities of behavioural activation therapy for depression (BATD):59,60 in-office or via videoconferencing to the patient’s home. The identification of differential treatment satisfaction and the characteristics of individuals who prefer one modality over the other will aid in the identification of the most suitable modality for delivery of BATD.
Methods
Participants
Active duty participants were recruited at a large regional military treatment facility located at Joint Base Lewis-McChord (JBLM) in Washington State, and veterans at the VA Health Care System (VAPHCS) in Portland, Oregon, USA. Participants were included in the study if they met Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) 61 diagnostic criteria for major depressive disorder or minor depressive disorder based on the Structured Clinical Interview for the DSM-IV Axis I Disorders, Research Version, Patient Edition (SCID-I/P 62 ). A complete description of the trial methodology is available in a previous publication, 63 as are the primary clinical outcomes associated with this trial. 64
Procedures
A study research coordinator conducted initial eligibility criteria screening via telephone. Eligible participants were scheduled to complete informed consent procedures and an in-person SCID-I/P with the study team’s independent clinical assessor. A total of 92 active duty and 29 veteran participants met all inclusion criteria and were randomized into two treatment groups, one receiving treatment in person at providers’ offices, and the other receiving treatment via videoconference in their own homes. Participants were randomized to treatment condition in a 1:1 ratio using block randomization of size 10, stratified by baseline major or minor depressive disorder diagnosis using Stata 12.1. 65 Participants randomized to the in-home condition were provided with a Dell M6500 laptop computer and Tandberg Precision High Definition webcam. The laptops were pre-loaded with Jabber video software.
Treatment protocol
An eight-session BATD protocol was used as the study’s intervention. 66 Both groups received the same BATD treatment for 50–60 min sessions every week for eight weeks with clinical assessments conducted at baseline, four-week midpoint, eight-week treatment completion and three-month follow-up. There were five doctoral level mental health treatment providers (four at JBLM and one at VAPHCS), who received training from a BATD expert and consultant. The fidelity reviews confirmed an overall adherence of 98.19% for all clinicians providing treatment.
Measures
Client Satisfaction Questionnaire (CSQ) 67
The CSQ-8 is an eight-item self-report measure of general satisfaction with psychotherapeutic treatment. Participants are asked to rate satisfaction on a four-point scale, with a possible range of 8–32, with higher scores indicating greater satisfaction. Internal consistency and construct validity have been established and the measure is widely used in research. The CSQ was administered at post treatment. Coefficient alpha for the measure was 0.91.
Other measures
Participants provided demographic information including occupation/work status/income/living situation, branch of service/highest rank, and medication use.
The Beck Hopelessness Scale (coefficient alpha = 0.91) 68 and the Beck Depression Inventory II (BDI-II; coefficient alpha = 0.95) 69 were the primary outcome measures for the original trial. Anxiety was assessed by the Beck Anxiety Inventory (coefficient alpha = 0.91), 70 posttraumatic stress syndrome (PTSD) by PTSD Checklist – Military version (coefficient alpha = 0.95), 71 loneliness using the De Jong Gierveld loneliness scale (coefficient alpha = 0.76) 72 and stigma using the Inventory of Attitudes toward Seeking Mental Health Services (coefficient alpha = 0.86). 73
Statistical analyses
We used the technique outlined by Kraemer 74 to identify moderation of treatment satisfaction. Unlike traditional testing of moderation using product terms for each moderator in a regression model, Kraemer’s technique derives a composite moderator of two or more underlying potential moderators. This approach improves the likelihood of identifying moderation with modest sample sizes that are underpowered to detect individual moderators in the traditional approach.
In the first phase of the analysis, the data were restructured to generate a dataset with all possible pairs of participants in one treatment group with those in the other. Differences scores were calculated for the satisfaction measure. For each of the candidate moderator variables, we calculated both a difference score and an average score. The difference score accounted for the main effect of the candidate moderator on the outcome; the average score was the effect of any moderation. The difference and average scores for each candidate moderator were used in separate regression models with the difference score for satisfaction as the outcome. From these models, we calculated the effect size of moderation for each candidate moderator. This effect size was the correlation between the satisfaction difference score and the candidate moderator average score. We used the 2.5 and 97.5 percentile effect size values of bootstrap resamples of the data to create the 95% confidence interval (CI) for each effect size estimate.
Candidate moderators were selected for inclusion in the composite moderator based on substantive considerations, individual effect size, and independent contribution to the composite. For the latter, we used a principal component analysis to identify orthogonal sets among the candidate moderator variables. This allowed us to create a better composite by minimizing shared variance and potential collinearity between the individual variables included. 75 After identifying the set of candidate moderators to be included in the composite moderator, we estimated a regression model in the all-possible-pairs dataset with the difference and average terms for each of the candidate variables included simultaneously. The coefficients for the average terms became the weights for generating the composite moderator.
We used a Tobit regression model to assess moderation using a product term of treatment assignment and the combined moderator in the original post-treatment dataset. We selected a Tobit model given the pronounced ceiling effect observed in the data. We generated regression lines of treatment satisfaction as a function of treatment assignment and composite moderator score to identify where the lines intersected. For descriptive purposes, we examined the distributions of the contributing moderators to the subsets of participants above and below the intersection point to identify possible differences for consideration in future research.
All models were estimated using Stata 13. 65 Categorical candidate moderator variables were effect coded (–.5, .5). All variables were standardized using the total sample distribution at post treatment. This facilitated direct comparison of the resulting effect size estimates. Bootstrap 95% CIs were generated using 1000 resamples of the data.
Results
Characteristics of participants who finished the study and provided information on client satisfaction, by assigned treatment group.
BAI: Beck Anxiety Inventory; BDI-II: Beck Depression Inventory II; BHS: Beck Hopelessness Scale; PCL: Posttraumatic stress syndrome Checklist.
Effect size and bootstrapped 95% confidence intervals of all potential moderators and the regression weights of moderators included in the composite moderator.
BAI: Beck Anxiety Inventory; BDI-II: Beck Depression Inventory II; BHS: Beck Hopelessness Scale; CI: confidence interval; PCL: Posttraumatic stress syndrome Checklist.
The final Tobit regression model identified a small interaction that was not statistically significant in that model at the conventional .05 level (b = 0.30, SE = –0.18, p = .111); however, the interaction effect size based on the all-possible-pairs dataset was 0.08 (95% CI = 0.06, 0.10). This effect size was comparable to that of the strongest individual contributing moderator. The composite moderator effect size did have a marginal improvement in precision over the individual moderator effect sizes. Figure 1 provides a graphical interpretation of the possible moderation effect. For those in the in-office treatment group, treatment satisfaction scores decreased with increasing scores on the moderator (b = −0.21, 95% CI = −0.48, 0.06); for those in the in-home group, there was a modest increase in treatment satisfaction scores (b = 0.09, 95% CI = −0.16, 0.33) as the moderator score increased. The two curves intersected at the mediator score value of 0.95. Participants with moderator scores below the intersection point had higher satisfaction scores for the in-office treatment modality. Those with moderator scores above the intersection point had higher satisfaction scores for the in-home modality.
Plot of satisfaction as a function of the composite moderator score, by treatment group.
Values of individual moderator variables included in the composite moderator (M) for individuals below and above the intersection point of the treatment group regression lines.
BDI: Beck Depression Inventory
Discussion
Patient satisfaction plays an important role in treatment outcome. Thus, it is not surprising that both clinical practitioners and researchers often include patient satisfaction with the treatment, the provider and the therapy results as one of the outcome measures.76,77 Importantly, O’Donoghue and colleagues 78 have shown that patient satisfaction data are comparable between clinical settings and research studies. The present study evaluated patient satisfaction in a group of current and former military personnel with depression who were participating in a randomized clinical trial using BATD delivered in-office and by videoconferencing to the home.63,64
In the present study, patient satisfaction was very high, with no significant differences between the treatment modalities. These findings are consistent with previous studies comparing in-person and telehealth treatments of mental health disorders.79–81 There were no significant differences in patient satisfaction between treatment sites or between different treatment providers, indicative of a comparable quality of care and a strong therapeutic allegiance developed between the participants and the providers, irrespective of the treatment modality. The two treatment modalities have different strengths and weaknesses. In-person BATD provides a traditional, in-office treatment with a richer communication environment (both verbal and non-verbal) than in-home treatment through telehealth. On the other hand, the in-home treatment modality may offset some of the potential missing aspects of the in-person treatment by enabling greater comfort due to the participants’ ability to relax in a familiar environment. This balance between the positive and negative aspects of the two modalities may explain the similarity in the levels of patient satisfaction observed in our study.
What is unique about the current investigation, however, is that rather than assessing change in satisfaction over the course of a standardized, eight session treatment protocol, this study attempted to identify which patients are likely to prefer either in-home or in-person treatment based on baseline characteristics. Contrary to popular beliefs about tech-savvy youth, higher end-of-treatment satisfaction for in-person care was most commonly associated with younger age and more junior military status. Conversely, higher end-of-treatment satisfaction for in-home care was more commonly associated with older, more senior, and more symptomatic service members. Given this distinction, the key question becomes: why? Plausible explanations for this profile difference include stigma, symptom severity and convenience.
Stigma. We typically assume that stigma prevents treatment-seeking behaviour, but what if it could also account for what treatment modalities patients express a preference for? Those who experience stigma about mental health services, but who are able to seek treatment regardless, may show an increased preference for in-home services, such as those in this investigation who represented an older, more senior demographic that may have experienced high degrees of stigma in the past prior to the military’s efforts to actively combat mental health stigma. Symptom severity. Perhaps those with more severe depression scores prefer in-home treatment because it does not force them to engage in the naturalistic behavioural activation required for in-office care. In this scenario, in-home treatment options are a double edged sword. One the one hand, they result in a stepped care approach where those who are unwilling to engage in in-office care may be willing to engage in home-based care. On the other hand, however, home-based care may facilitate avoidance and disconnection from the naturalistic reinforcement of functional behaviour that occurs when an individual takes the activating steps required to attend an office appointment (e.g. engaging in personal hygiene routine, grooming one’s self, getting dressed, driving, interacting with others, etc.). Convenience. Convenience has long been cited as a potential benefit for telehealth. For example, retired military veterans who reside several hours away from the nearest VA Hospital may be especially interested in remote care. But what about active duty service members who typically live on or very near the military installation to which they are assigned? Convenience becomes more than travel time or cost. It has to do with time off/away from work, arrangement of child care services, managing a rigid schedule, et cetera. Given this, it is not surprising that the veterans included in this study were more satisfied with in-home services as they may have appealed to their needs and challenges. Conversely, those still in service may be navigating a different set of demands that were better suited to traditional care models.
While we cannot say which, or if any, of these issues accounts for the differences observed, this study stresses the importance of knowing what preferences are likely to be influencing a patient’s treatment-seeking behaviour and experience. In this case, basic demographic characteristics may influence the satisfaction that a patient may experience when receiving either home based or in-office care.
There are some key limitations to consider in this study. First, the power to detect a statistical interaction was low. This was reflected in the lack of traditional statistical significance of the interaction product term in the regression model. However, the use of bootstrapping for the overall effect size did provide a CI that did not cover the null value. At best, this suggests weak evidence for an interaction that would need to be studied more in depth in a larger study. Second, the generation of a linear combination moderator variable improved our ability to identify a possible interaction; however, this came at the cost of identifying which particular variable(s) ultimately produce the observed differential response in treatment satisfaction. Another consideration associated with the linear combination is that the composition of the linear combination in terms of both variables and the associated weights was determined from the dataset used in the final analysis. This means that what was observed in these data may not replicate in an independent dataset. Finally, the description of groups based on the intersection point of the interaction is not inferential. This description can inform hypothesis generation for additional study, but it is not in and of itself strong evidence that individuals with these characteristics will exhibit a strong preference for one modality over another.
The construct of satisfaction is complex, and when applied to clinical intervention, that complexity is amplified. However, as technology allows the application of more diverse and unfamiliar treatment modalities, clinicians need to be aware of how those modalities may be received by their patients. This study provides insight into how basic demographic characteristics can help target particular intervention modalities based on the satisfaction a service member or veteran may experience when seeking treatment for depression. Junior patients or those with less severe symptoms may be more satisfied with traditional care models, while more senior or more symptomatic patients may prefer home-based care.
Footnotes
Acknowledgement
The content of this information does not necessarily reflect the position or the policy of the United States Government, and no official endorsement should be inferred.
Declaration of Conflicting Interests
The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Funding
The author(s) received no financial support for the research, authorship, and/or publication of this article.
