Coronary risk factors in middle-aged men as related to smoking,coffee intake and physical activity

Abstract

Coronary risk factors in middle-aged men as related to smoking, coffee intake and physical activity. Høstmark, A. T., Berg, J., Brudal, S., Berge, S., Kierulf, P. and Bjerkedal, T. (Department of Preventive Medicine, University of Oslo, Occupational Health Service for STK-Alcatel, and Oslo Transport. Research Group, Central Laboratory, Ullevål Hospital, Oslo).

The relationship between lifestyle and coronary risk factors in blood was investigated in 165 middle-aged men. Plasma fibrinogen, serum triacylglycerols (TG), and apolipoprotein B (apo B) were higher, and high density lipoprotein cholesterol (HDLc) lower in smokers (n = 69) than in non-smokers (n = 96). By linear regression analysis there was a significant positive association between degree of smoking and either total cholesterol (TC), apo B, or plasma fibrinogen, whereas smoking was inversely related to HDLc.

Smoking and coffee intake were positively correlated with an atherogenic index, reflecting the balance between low and high density lipoproteins. Sedentary men (n = 59) had higher mean TC, apo B, and atherogenic index than physically active men (n = 104). Smokers used salt more often than non-smokers. Physically active men used vegetables more often than sedentary men. Combining several habits into a “badhabit” score gave a high level of significance for its association with TC, apo B, and the atherogenic index. The results indicate that lifestyle may influence several blood factors involved in atherosclerosis development.

Keywords

lifestyle factors smoking coffee physical activity fibrinogen triacylglycerols apolipoproteins

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