Biological Interpretation of the Correlation of Emergence Times of Permanent Teeth

Abstract

The eruption mechanism is not fully understood. It is known that the dental follicle is essential and that experimentally provoked denervation influence the process of eruption. Accordingly, the purpose of this study was to elucidate the eruption pattern in a human population and relate this pattern to the pattern of jaw innervation. The eruption pattern was evaluated from the correlation between the emergence times of different teeth in the permanent dentition based on longitudinal data from a large national registry (12,642 boys and 12,095 girls). Correlations coefficients were generally high (>0.5) and higher between teeth within the same tooth groups (i.e. incisors, canines and premolars, and molars) than between teeth from different tooth groups. It was shown that the correlation in emergence of teeth closely followed the pattern of innervation of the jaws. Thus the study supported the hypothesis concerning a possible association between eruption and innervation.

Get full access to this article

View all access options for this article.

References

Chavéz-Loméli ME, Mansilla Lory J, Pompa JA, Kjær I -1996-. The human mandibular canal arises from three separate canals innervating different tooth groups. J Dent Res 75:1540–1544.

Christensen LR, Janas MS, Møllgård K, Kjær I -1993-. An immunocytochemical study of the innervation of developing human fetal teeth using protein gene product 9.5 -PGP 9.5-. Arch Oral Biol 38:1113–1120.

Garn SM, Smith BH -1980-. Developmental communalities in tooth emergence timing. J Dent Res 59:1178.

Garn SM, Lewis AB, Polacheck DL -1960-. Interrelations in dental development. I. Interrelations within the dentition. J Dent Res 39:1049–1055.

Hamano Y, Hägg U -1988-. Inter-relationships among ages of emergence of teeth. A prospective longitudinal study of Swedish children from birth to 18 years. Eur J Orthod 10:273–280.

Kent RL Jr, Reed RB, Moorrees CF -1978-. Associations in emergence age among permanent teeth. Am J Phys Anthropol 48:131–142.

Kjær I -1995-. Human prenatal craniofacial development related to brain development under normal and pathologic conditions. Acta Odontol Scand 53:135–143.

Kjær I -1997-. Can the location of tooth agenesis and the location of initial bone loss seen in juvenile periodontitis be explained by neural developmental fields in the jaws? Acta Odontol Scand 55:70–72.

Lindsey JC, Ryan LM -1998-. Tutorial in biostatistics methods for interval-censored data. Stat Med 17:219–238.

10.

Mardia KV, Kent JT, Bibby JM -1979-. Multivariate analysis. London: Academic Press.

11.

Marks SC Jr, Schroeder HE -1996-. Tooth eruption: theories and facts. Anat Rec 245:374–393.

12.

Parner ET -2001-. Non-parametric maximum likelihood estimation for bivariate interval censored data. Research report. Aarhus: Department of Biostatistics, University of Aarhus.

13.

Parner ET, Heidmann JM, Væth M, Poulsen S -2001-. A longitudinal study of time trends in the eruption of permanent teeth in Danish children. Arch Oral Biol 46:425–431.

14.

Sturdivant JE, Knott VB, Meredith HV -1962-. Interrelations from serial data for eruption of the permanent dentition. Angle Orthod 32:1–13.

15.

Varpio M, Wellfelt B -1988-. Disturbed eruption of the lower second molar: clinical appearance, prevalence, and etiology. ASDC J Dent Child 55:114–118.

16.

Yamashiro T, Fujiyama K, Fujiyoshi Y, Inaguma N, Takano-Yamamoto T -2000-. Inferior alveolar nerve transection inhibits increase in osteoclast appearance during experimental tooth movement. Bone 26:663–669.