Objectives. A cross-sectional study was conducted to assess the prevalence of human immunodeficiency virus (HIV), hepatitis B virus (HBV), and their coinfection among blood donors at the National Blood Transfusion Center in Bamako, Mali, from November 2001 to July 2002. Methods. Enzyme-linked immunosorbent assay techniques with reagents from Bio-Rad (France) were used to test the blood samples. Results. 11 592 blood donors were tested for HIV and HBV surface antigens. The prevalence of HIV was 4.5% and the prevalence of HBV was 14.9%. The HIV/HBV coinfection rate was only 1.13% in this population. Conclusion. The coinfection rate was unexpectedly low in this blood donor population where monoinfection with HIV or HBV prevalence was high.
Center for Disease Control and Prevention.Geographical distribution of Hepatitis B [online]. September 25 2007; Available at: http://www.cdc.gov/ncidod/diseases/hepatistis/slidesset/hep_b/slide_9htm . Accessed February 21, 2008.
2.
Lok A., McMahon B.Chronic hepatitis B. Hepatology. 2001 ;34:1225-1241.
3.
Modi AA, Feld JJViral hepatitis and HIV in Africa. AIDS Rev. 2007;9:25-39.
4.
Tembely K.Transaminase Enzymes Determination in Blood Donors at Bamako's Blood Bank . Bamako, Mali: FMPOS Thesis of pharmacist; 2002.
5.
Unaid.AIDS Epidemic Update. Geneva, IN; 2007.
6.
Ministry of Health of Mali.National Demographics Survey for Health (EDSM-IV). Bamako, Mali; 2007.
7.
Weber R., Sabin CA, Friis-Moller N., et al. Liver-related deaths in persons infected with human immunodeficiency virus; the D:A:D study. Arch Intern Med. 2006 ;166: 1632-1641.
8.
Graham CS, Baden LR, Yu E., et al. Influence of human immuno deficiency virus infection on the course of Hepatitis C virus infection: a meta analysis. Clin Infect Dis. 2001;33:562-569.
9.
Sulkowski MSViral hepatitis and HIV coinfection. J Hepatol. 2008;48:353-367.
10.
Forbi JC, Gabadi S., Alabi R., et al. The role of triple infection with hepatitis B virus, Hepatitis C virus, and Human immunodeficiency virus (HIV) type-1 on CD-4+ lymphocyte levels in highly HIV infected population of North-Central Nigeria. Mem Inst Oswaldo Cruz. 2007;102: 535-537.
11.
Christine Kukka.HIV/HBV: coinfection. What you need to know?HCSPFACTsheet version 1.0 February 2004.
12.
Peter.Diagnostic and Management of Hepatitis B virus and HIV coinfection. Top HIV Med. 2007;15:163-166.
13.
Kiemtore Pmng .Antibodies Against Toxoplasma in Blood Donors and HIV Infected Patients at Bamako. Bamako, Mali: FMPOS Pharmacist thesis N°12; 1998.
14.
Soureya Z.Screening of HIV in Blood Donors at the National Blood Transfusion Center of Bamako, Mali. Bamako, Mali: FMPOS Thesis of pharmacist N°9; 2001.
15.
Traore B.Epidemiological Results After Using Five Methods of HIV Screening at National Blood Transfusion Center, Bamako. Bamako, Mali : FMPOS Thesis of Pharmacist; 2002 .
16.
Yerbanga FXHepatitis B Surface Antigen in Blood and Hematological Parameters in Blood Donors Population at Bamako. Bamako, Mali: FMPOS Thesis of pharmacist; 1997.
17.
Boyeldieu D. , Thiam D., Diakhaté L.Blood transfusion safety in Senegal. SIDA Alerte. 1995;43:26-27.
18.
Kourouma K.Blood transfusion in Guinea National blood transfusion center. SIDA Alerte Mai. 1995;43: 27-28.
19.
Egah DZ, Banwat EB, Audu ES, et al. Hepatitis B surface antigen, hepatitis C and HIV antibodies in low-risk blood donor group, Nigeria. East Mediterr Heath J. 2007;13:961-966.
20.
Mecky IN, Matee, Pius M Magesa, and Eligius F Lyamuya.Seroprevalence of human immunodeficiency virus, Hepatitis B and C viruses and Syphilis infections among blood donors at the Muhimbili National Hospital in Dar Es Salaam, Tanzania . BMC Public Health2006; 6:21.
21.
Ellen Collenberg , Thierry Ouedraogo, Jean Ganame, Helmut Fickenscher, Gisela Kynast-Wolf, Heiko Becher, Bocar Kouyate, Hans-Georg Krä usslich, Lassana Sangare, and Denis M. Tebit .Seroprevalence of Six Different Viruses Among Pregnant Women and Blood Donors in Rural and Urban Burkina Faso: A Comparative Analysis. J Med Virol.2006;78:683-692.
22.
Lina Cunha , Chloé Plouzeau, Pierre Ingrand, et al. Use of Replacement Blood Donors to Study the Epidemiology of Major Blood-Borne Viruses in the General Population of Maputo, Mozambique. J Med Virol.2007;79: 1832-1840.
23.
Tswana S., Chetsanga C., Nystrom L., Moyo S., Nzara M., Chieza LASero-epidemiological cross-sectional study of hepatitis B virus in Zimbabwe . S Afr Med J. 1996;86: 72-75.
24.
Batina A., Kabemba S., Malengela R.Infectious markers among blood donors in Democratic Republic of Congo (DRC) . Rev Med Brux. 2007;28:145-149.
25.
Zekeng L., Kaptue L.Serology of HIV1 and carriage of HVB surface antigen and Hbe antibodies in blood donors at CHU of Yaounde, Cameroun. Ann Soc Belg MedTrop . 1990;70:49-53.
26.
Yala F., Olembe C., M'Pele P., Rosenheim M.HVB surfaces antigen, HIV antibodies carriage and their association in blood donors in Brazzaville. Bull Soc Pathol Exot.1988;81:32-39.
27.
Zawde D., Sisay Y.National blood requirement, serum ALT and hepatitis in Ethiopian blood donors . Ethiop Med J.175-183.
28.
Ejele O., Nwauche C., Erhabor O.The prevalence of Hepatitis B surface antigenemia in HIV-positive patients in The Niger Delta Nigeria. Niger J Med. 2004 ;13:175-179.
29.
Uneke C., Ogbu O., Inyama P., Anyanwu G., Njoku M., Idoko J.Prevalence of Hepatitis-B surface antigen among blood donor and HIV infected patients in Jos, Nigeria. Mem Inst Oswaldo Cruz. 2005;100:13-16.
30.
Matee M., Magesa P., Lyamuya E.Prevalence of HIV, Hepatitis B and C viruses and syphilis infections among blood donors at the Muhimbili National Hospital in Dar es Salaam, Tanzania . BMC Public Health.2006; 6-21.
31.
Matee M., Lyamuya E., Mbena E., et al. Prevalence of transfusion associated viral infections and syphilis among blood donors in Muhimbili Medical Center, Dar es Salaam, Tanzania. East Afr Med J. 1999;76:167-71.
