Management of Native Lung Malignancy in a Lung Transplant Recipient

Abstract

A 75-year-old male patient with a history of previous right lung transplant presented with left upper lobe squamous cell carcinoma. Endobronchial ultrasound and positron emission tomography displayed no mediastinal lymphadenopathy. A ventilation-perfusion scan displayed minimal perfusion to the native lung. Left robot-assisted lysis of adhesions, decortication, left upper lobectomy, and mediastinal lymphadenectomy were performed. The patient tolerated the procedure well. Final pathology displayed pT2a, n0, m0. Lobectomy is a safe and efficient treatment of native lung malignancy in the setting of previous lung transplant with minimally functioning native lung.

Keywords

lung transplant lung cancer robotic surgery lobectomy lung squamous cell carcinoma

Get full access to this article

View all access options for this article.

References

Mathew

Kratzke

. Lung cancer and lung transplantation: a review. J Thorac Oncol 2009; 4: 753–760.

Shtraichman

Ahya

. Malignancy after lung transplantation. Ann Transl Med 2020; 8: 416.

Chambers

Cherikh

Harhay

, et al. The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: thirty-sixth adult lung and heart-lung transplantation report-2019; focus theme: donor and recipient size match. J Heart Lung Transplant 2019; 38: 1042–1055.

Pennell

Elson

, et al. Lung cancer treatment outcomes in recipients of lung transplant. Transl Lung Cancer Res 2015; 4: 784–791.

Raviv

Shitrit

Amital

, et al. Lung cancer in lung transplant recipients: experience of a tertiary hospital and literature review. Lung Cancer 2011; 74: 280–283.

Espinosa

Baamonde

Illana

, et al. Lung cancer in patients with lung transplants. Transplant Proc 2012; 44: 2118–2119.

Grewal

Padera

Boukedes

, et al. Prevalence and outcome of lung cancer in lung transplant recipients. Respir Med 2015; 109: 427–433.

Aryal

Nathan

. Single vs. bilateral lung transplantation: when and why. Curr Opin Organ Transplant 2018; 23: 316–323.

Puri

Patterson

Meyers

. Single versus bilateral lung transplantation: do guidelines exist? Thorac Surg Clin 2015; 25: 47–54.

10.

Takahashi

Terada

Pasque

, et al. Clinical features and outcomes of combined pulmonary fibrosis and emphysema after lung transplantation. Chest 2021; 160: 1743–1750.

11.

Hage

Gautschi

Steinack

, et al. Combined pulmonary fibrosis and emphysema (CPFE) clinical features and management. Int J Chron Obstruct Pulmon Dis 2021; 16: 167–177.

12.

Antończyk

Stącel

Urlik

, et al. Single lung transplant vs double lung transplant: a single-center experience with particular consideration for idiopathic pulmonary arterial hypertension. Transplant Proc 2020; 52: 2138–2142.

13.

Gherzi

Carillo

Diso

, et al. Devastating fast-growing lung cancer after single lung transplantation. J Thorac Dis 2017; 9: E1071–E1073.

14.

King

Khandhar

Burton

, et al. Native lung complications in single-lung transplant recipients and the role of pneumonectomy. J Heart Lung Transplant 2009; 28: 851–856.

Supplementary Material

Please find the following supplemental material available below.

For Open Access articles published under a Creative Commons License, all supplemental material carries the same license as the article it is associated with.

For non-Open Access articles published, all supplemental material carries a non-exclusive license, and permission requests for re-use of supplemental material or any part of supplemental material shall be sent directly to the copyright owner as specified in the copyright notice associated with the article.

0.00 MB

0.16 MB