Traumatic dental lesions are more frequently found in the pediatric population, with a major involvement, in 80% of the cases, of the superior central incisors. The exposure of the dental pulp leads to major morphological changes in dental tissue, such as discolouring, acute pulp inflammation, chronic inflammation and necrosis. This article reviews the various studies published on the different types of inflammatory response of the pulp tissue following traumatic events, from the microbiological and histological point of view of various techniques.
Al-MajedI.MurrayJ.J.MaguireA.2000. Prevalence of dental trauma in 5–6 and 12–14 year-old boys in Riyadh, Saudi Arabia. Dent. Traumatol.17:153.
2.
BradfordI.2002. Dental Emergencies presenting to a dental teaching hospital due to complications from traumatic dental injuries. Al-Jundi Dental Trauma18:181.
3.
AndreasenJ.O.AndreasenF.M.1994. Classification, etiology and epidemiology of traumatic dental injuries. In Textbook and color atlas of traumatic injuries to the teeth, 3d ed.AndreasenJ.O.AndreasenF.M., eds. Munksgaard, Copenhagen, p. 151.
4.
McTigueD.J.2000. Diagnosis and management of dental injuries in children. Pediatr. Clin. North Am.47:1067.
5.
PugliesiD.M.CunhaR.F.DelbemA.C.SudenfeldM.L.2004. Influence of type of dental trauma on the pulp vitality and the time elapsed until treatment: A study in patients aged 0–3 years. Dent. Traumatol.20:139.
6.
SandalliN.CildirS.GulerN.2005. Clinical investigation of traumatic injuries in Yeditepe University, Turkey during the last 3 years. Dent. Traumatol.21:188.
7.
JankS.Maurer-StockingerB.S.EmshoffR.RothlerG.StroblH.WaldhartE.2001. Long-term outcome of dentoalveolar trauma in relation to post-traumatic instability. Mund Kiefer Gesichtschir.5:348.
8.
DiabM.elBradwayH.E.2000. Intrusion injuries of primary incisors. Part II: Sequelae affecting the intruded primary incisors. Quintessence Int.31:335.
9.
CvekM.1994. Endodontic management of traumatized teeth. In Texbook and color atlas of traumatic injuries to the teeth, 3rd edn.AndreasenJ.O.AndreasenF.M., ed. Munksgaard-DKK, Copenhagen, p.517.
10.
SoxmanJ.A.NazifM.M.BouquotJ.1984. Pulpal pathology in relation to discoloration of primary anterior teeth. ASDC J. Dent. Child.51:282.
11.
RaslanN.WetzelW.E.2006. Exposed human pulp caused by trauma and /or caries in primary dentition: A histological evaluation. Dent. Traumatol.22:145.
12.
CaliskanM.K.OztopF.CaliskanG.2003. Histological evaluation of teeth with hyperplastic pulpitis caused by trauma or caries: Case reports. Int. Endod. J.36:64.
13.
NishimuraY.MiuraY.MaedaM.HayashiH.DongM.KatsuyamaH.TomitaM.HyodohF.KusakaM.UesakaA.KuribayashiK.FukuokaK.NakanoT.KishimotoT.OtsukiT.2006. Expression of the T cell receptor Vβ repertoire in a human T cell resistant to asbestos-induced apoptosis and peripheral blood T cells from patients with silica and asbestos-related diseases. Int. J. Immunopathol. Pharmacol.19:795.
14.
ManouryB.Caulet-MaugendreS.GuénonI.LagenteV.BoichotE.2006. TIMP-1 is a key factor of fibrogenic response to bleomycin in mouse lung. Int. J. Immunopathol. Pharmacol.19:471.
15.
CastellaniM.L.SaliniV.FrydasS.DonelanJ.TagenM.MadhappanB.PetrarcaC.FalascaK.NeriG.Tete'S.VecchietJ.2006. The proinflammatory interleukin-21 elicits anti-tumor response and mediates autoimmunity. Int. J. Immunopathol. Pharmacol.19:247.
16.
CrollT.P.PasconE.A.LangelandK.1987. Traumatically injured primary incisors: A clinical and histological study. ASDC J. Dent. Child.54:401.
17.
Harran-PonceE.HollandR.Barreiro-LoisA.Lopez-BeceiroA.M.EspinelJ.L. Pereira. 2002. Consequences of coronal fractures with pulpal exposure: Histopathological evaluation in dogs. Dent. Traumatol.18:196.
18.
JinH.ThomasH.F.ChenJ.1996. Wound healing and revascularization: A histologic observation of experimental tooth root fracture. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod.81:26.
19.
CaliskanM.K.SepetciogluF.1993. Partial pulpotomy in coronal-fractured permanent incisor with hyperplastic pulpitis: A case report. Endod. Dent. Traumatol.9:171.
20.
LangS.PicuA.HofmannT.AndratschkeM.MackB.MoosmannA.GiresO.TiwariS.ZeidlerR.2006. Cox-inhibitors relieve the immunosuppressive effect of tumor cells and improve functions of immune effectors. Int. J. Immunopathol. Pharmacol.19:409.
21.
TrubianiO.OrsiniG.CaputiS.PiattelliA.2006. Adult mesenchymal stem cells in dental research: A new approach for tissue engineering. Int J Immunopathol Pharmacol.19:451.
22.
VenaG.A.CassanoN.AlessandriniG.FaiD.GabelloneM.LigoriP.MalvindiC.MancinoA.PellèS.RinaldiF.SodoM.R.2007. Treatment of mild to moderate plaque psoriasis with calcitriol ointment applied with or without a dosing device. Eur. J. Inflamm.5:89.
ByersM.R.1992. Effects of inflammation on dental sensory nerves and vice versa. Proc. Finn. Dent. Soc.88(S):499.
28.
WoodnuttD.A.Wager-MillerJ.O'NeillP.C.BothwellM.ByersM.R.2000Neurotrophin receptors and nerve growth factor are differentially expressed in adjacent non-neuronal cells of normal and injured tooth pulp. Cell Tissue Res.299:225.
29.
TakahashiK.1990. Changes in the pulpal vasculature during inflammation. J. Endo.16:92.
30.
KimS.1990. Neurovascular interactions in the dental pulp in health and inflammation. J. Endod.16:48.
31.
WakisakaS.1990. Neuropeptides in the dental pulp: Distribution, origins, and correlation. J. Endod.16:67.
32.
SchiavinoD.NuceraE.AlonziC.BuonomoA.PollastriniE.RoncalloC.De PasqualeT.LombardoC.La TorreG.SabatoV.PecoraV.PatriarcaG.2006. A clinical trial of oral hyposensitization in systemic allergy to nickel. Int. J. Immunopathol. Pharmacol.19:593.
33.
FerriniA.M.MannoniV.AureliP.SalvatoreG.PiccirilliE.CeddiaT.PontieriE.SessaR.OlivaB.2006. Melaleuca alternifolia essential oil possesses potent anti-staphylococcal activity extended to strains resistant to antibiotics. Int. J. Immunopathol. Pharmacol.19:539.
34.
CadoniS.RuffelliM.FusariS.de PitàO.2007. Oral allergic syndrome and recombinant allergens rBet v 1 and rBet v 2. Eur. J. Inflamm.5:21.
35.
BehniaA.ZhangL.CharlesM.GoldM.S.2003. Changes in TrkB-like immunoreactivity in rat trigeminal ganglion after tooth injury. J. Endod.29:135.
36.
HerreraD.RoldanS.SanzM.2000. The periodontal abscess: A review. J. Clin. Periodontol.27:377.
37.
TrummelC.L.BehniaA.2002. Periodontal and pulpal infections. In Oral and maxillofacial infections4th ed.TopazianR.G.GoldbergM.H.HuppJ. R., eds. Saunders, Philadelphia, p.126.
38.
StashenkoP.TelesR.D'SouzaR.1998. Periapical inflammatory responses and their modulation. Crit. Rev. Oral Biol. Med.9:498.
39.
RobertsonA.AndreasenF.M.AndreasenJ.O.NorenJ.G.2000. Long term prognosis of coronal-fractured permanet incisors. The effect of stage of root development and associated luxation injury. Int. J. Paediatric Dentistry10:191.
40.
LakotaK.Mrak-PoljšakK.RozmanB.KvederT.TomšičM.Sodin-SemrlS.2007. Serum amyloid A activation of inflammatory and adhesion molecules in human coronary artery and umbilical vein endothelial cells. Eur. J. Inflamm.5:73.
41.
LoveR.M.JenkinsonH.F.2002. Invasion of dentinal tubules by oral bacteria. Crit. Rev. Oral Biol. Med.13:171.
42.
OlsburghS.KrejciI.2003. Pulp response to traumatic coronal fractures. Endodontic Topics5:26.