Abstract
Answer C. Co-prescription of isosorbide mononitrate
First-line pharmacological treatment of erectile dysfunction is with phosphodiesterase-5 inhibitors. Contra-indications include nitrate prescription, patients for whom sexual activity is not advisable, history of non-arteritic optic neuropathy, severe hepatic disorders, retinal degeneration, end-stage renal disease requiring dialysis (vardenafil only), use of indinavir/ketoconazole/itraconazole in patients over age 75 years (vardenafil only), heart failure and uncontrolled arrhythmia/hypertension (tardalafil only). The rest of the options require caution only with prescribing of phosphodieasterase-5 inhbitors.
InnovAiT article: Erectile dysfunction. DOI: 10.1177/1755738018759373.