Abstract
Answer A. Aim to lose 5–10% of starting weight before the pregnancy
Being obese (body mass index >30 kg/m2) while pregnant is associated with an increased risk of many pregnancy complications, including miscarriage, gestational diabetes (GDM), pre-eclampsia, prematurity, stillbirth and delivery complications. Trying to lose weight during pregnancy is not recommended, so the pre-conception period is the best opportunity to address these risks and improve the chances of conception. While achieving a healthy weight (body mass index of 18.5–24.9) is the ideal, such patients should aim to lose 5–10% of their starting weight as a realistic target. Glucagon-like peptide 1 agonists are not advised for use during pregnancy or when trying to conceive, and for some, the manufacturer recommends delaying pregnancy for a period of time after stopping. Orlistat, another commonly used weight-loss medication, should be used with caution during pregnancy.
InnovAiT article: Pre-conception counselling. DOI: 10.1177/17557380241235648.