MR Imaging of Hippocampal Sulcus Remnant: Age-Related Differences

Abstract

The hippocampal sulcus remnant (HSR) is often observed at the medial temporal lobe on MR images. In the present study, we made a retrospective assessment of the frequency and age-related differences in HSR in routine brain MR examinations of 1000 patients, 494 females and 506 males. Cases with one or several spots that were hypointense on T1-weighted and FLAIR images and hyperintense on T2-weighted images were defined as positive for HSR. Abnormal spots with the same intensity as cerebrospinal fluid were observed in 210 out of 506 males and in 193 out of 494 females. No significant sex-related differences were observed in the frequency of HSR. The HSR was seen more frequently with age in both males and females. Patients with hypertension had a significantly higher frequency of HSR.

Keywords

hippocampal sulcus remnant perivascular space MR imaging aging

Get full access to this article

View all access options for this article.

References

Sasaki

Sone

: Hippocampal sulcus remnant: Potential cause of change in signal intensity in the hippocampus. Radiology 188: 743–746, 1993.

Williams

: Gray's anatomy 38th ed. Churchill Livingstone, New York, 1993: 1123–1126.

Kier

Kim

: Embryology of the human fetal hippocampus: MR imaging, anatomy, and histology. Am J Neuroradiol 18: 525–532, 1997.

Norman

McGillivray

: Congenital malformation of the brain Pathological, embryological, clinical, radiological and genetic aspects. Oxford, New York, 1995: 39.

Yoneoka

Kwee

: Criteria for normalcy of cavities observed within the adult hippocampus: High-resolution magnetic resonance imaging study on a 3.0-T system. J Neuroimaging 12: 231–236, 2002.

Cole

Yates

: Comparative incidence of cerebrovascular lesions in normotensive and hypertensive patients. Neurology 18: 255–259, 1968.

Braffman

Zimmerman

: Brain MR: Pathologic correlation with gross and histopathology. 1.lacunar infarction and Virchow-Robin spaces. Am J Neuroradiol 9: 621–628, 1988.

Heier

Bauer

: Large Virchow-Robin Spaces: MR-clinical correlation. Am J Neuroradiol 10: 929–936, 1989.

Bastos

Andermann

: Late-onset temporal lobe epilepsy and dilatation of the hippocampal sulcus by an enlarged Virchow-Robin space. Neurology 50: 784–787, 1998.

10.

Marinkovic

Milisavljevic

: Microvascular anatomy of the hippocampal formation. Surg Neurol 7: 339–349, 1992.

11.

Erdem

Yasargil

: Microsurgical anatomy of the hippocampal arteries. J Neurosurg 79: 256–265, 1993.