Studying Ultra-Complex Crude Oil Mixtures by Using High-Field Asymmetric Waveform Ion Mobility Spectrometry (FAIMS) Coupled to an Electrospray Ionisation-LTQ-Orbitrap Mass Spectrometer
Restricted accessResearch articleFirst published online February, 2014
Studying Ultra-Complex Crude Oil Mixtures by Using High-Field Asymmetric Waveform Ion Mobility Spectrometry (FAIMS) Coupled to an Electrospray Ionisation-LTQ-Orbitrap Mass Spectrometer
High-field asymmetric waveform ion mobility spectrometry (FAIMS) was coupled directly to an LTQ Orbitrap mass spectrometer to analyze a nitrogen-rich crude oil. Analyzing crude oil is extremely difficult because of the complexity, as up to 100,000 different components can be present. Therefore, simplification of crude oil increases the information content because discrimination and suppression effects are reduced. Here, the first results are presented that show that FAIMS can be an important tool for the simplification of complex mixtures. Additionally, the results show that FAIMS is an excellent tool that allows not only a simplification of such complex mixtures, but also shows the separation of isomeric compounds that have the same elemental composition but different structure and conformation.
ChoY.J.NaJ.G.NhoN.S.KimS.KimS., “Application of saturates, aromatics, resins, and asphaltenes crude oil fractionation for detailed chemical characterization of heavy crude oils by fourier transform ion cyclotron resonance mass spectrometry equipped with atmospheric pressure photoionization”, Energy Fuels26, 2558 (2012). doi: https://dx-doi-org.web.bisu.edu.cn/10.1021/ef201312m
6.
GasparA.ZellermannE.LababidiS.ReeceJ.SchraderW., “Characterization of saturates, aromatics, resins, and asphaltenes heavy crude oil fractions by atmospheric pressure laser ionization Fourier transform ion cyclotron resonance mass spectrometry”, Energy Fuels26, 3481 (2012). doi: https://dx-doi-org.web.bisu.edu.cn/10.1021/ef3001407
7.
PandaS.K.SchraderW.AnderssonJ.T., “β-cyclodextrin as a stationary phase for the group separation of polycyclic aromatic compounds in normal-phase liquid chromatography”, J. Chromatogr. A1122, 88 (2006). doi: https://dx-doi-org.web.bisu.edu.cn/10.1016/j.chroma.2006.04.026
8.
PandaS.K.SchraderW.al-HajjiA.AnderssonJ.T., “Distribution of polycyclic aromatic sulfur heterocycles in three Saudi Arabian crude oils as determined by Fourier transform ion cyclotron resonance mass spectrometry”, Energy Fuels21, 1071 (2007). doi: https://dx-doi-org.web.bisu.edu.cn/10.1021/ef060511s
9.
SchadeT.RoberzB.AnderssonJ.T., “Polycyclic aromatic sulfur heterocycles in desulfurized diesel fuels and their separation on a novel palladium(ii)-complex stationary phase”, Polycycl. Aromat. Compd22, 311 (2002). doi: https://dx-doi-org.web.bisu.edu.cn/10.1080/10406630290026975
10.
MullerH.AnderssonJ.T.SchraderW., “Characterization of high-molecular-weight sulfur-containing aromatics in vacuum residues using Fourier transform ion cyclotron resonance mass spectrometry”, Anal. Chem.77, 2536 (2005). doi: https://dx-doi-org.web.bisu.edu.cn/10.1021/ac0483522
11.
QianK.N.DechertG.J., “Recent advances in petroleum characterization by GC field ionization time-of-flight high-resolution mass spectrometry”, Anal. Chem.74, 3977 (2002). doi: https://dx-doi-org.web.bisu.edu.cn/10.1021/ac020166d
BuryakovI.A.KrylovE.V.NazarovE.G.RasulevU.K., “A new method of separation of multi-atomic ions by mobility at atmospheric pressure using a high frequency amplitude–asymetric strong electric field”, Int. J. Mass Spectrom. Ion Processes128, 143 (1993). doi: https://dx-doi-org.web.bisu.edu.cn/10.1016/0168-1176(93)87062-w
GuevremontR., “High-field asymmetric waveform ion mobility spectrometry (FAIMS)”, Can. J. Anal. Sci. Spectrosc.49, 105 (2004).
19.
GuevremontR.ThekkadathG.HiltonC.K., “Compensation voltage (CV) peak shapes using a domed FAIMS with the inner electrode translated to various longitudinal positions”, J. Am. Soc. Mass Spectrom.16, 948 (2005). doi: https://dx-doi-org.web.bisu.edu.cn/10.1016/j.jasms.2005.03.001
20.
ShvartsburgA.A.BryskiewiczT.PurvesR.W.TangK.Q.GuevremontR.SmithR.D., “Field asymmetric waveform ion mobility spectrometry studies of proteins: Dipole alignment in ion mobility spectrometry?”, J. Phys. Chem. B110, 21966 (2006). doi: https://dx-doi-org.web.bisu.edu.cn/10.1021/jp062573p
21.
GilesK.PringleS.D.WorthingtonK.R.LittleD.WildgooseJ.L.BatemanR.H., “Applications of a travelling wave-based radio-frequencyonly stacked ring ion guide”, Rapid Commun. Mass Spectrom.18, 2401 (2004). doi: https://dx-doi-org.web.bisu.edu.cn/10.1002/rcm.1641
22.
PringleS.D.GilesK.WildgooseJ.L.WilliamsJ.P.SladeS.E.ThalassinosK.BatemanR.H.BowersM.T.ScrivensJ.H., “An investigation of the mobility separation of some peptide and protein ions using a new hybrid quadrupole/travelling wave IMS/oa-ToF instrument”, Int. J. Mass Spectrom.261, 1 (2007). doi: https://dx-doi-org.web.bisu.edu.cn/10.1016/j.ijms.2006.07.021
23.
Fernandez-LimaF.A.BeckerC.McKennaA.M.RodgersR.P.MarshallA.G.RussellD.H., “Petroleum crude oil characterization by IMS-MS and FTICR MS”, Anal. Chem.81, 9941 (2009). doi: https://dx-doi-org.web.bisu.edu.cn/10.1021/ac901594f
24.
LababidiS.PandaS.K.AnderssonJ.T.SchraderW., “Direct coupling of normal-phase high-performance liquid chromatography to atmospheric pressure laser ionization Fourier transform ion cyclotron resonance mass spectrometry for the characterization of crude oil”, Anal. Chem.85, 9478 (2013). doi: https://dx-doi-org.web.bisu.edu.cn/10.1021/ac400670s
