The Influence of Spectral Resolution on the Quantitative near Infrared Spectroscopic Determination of an Active Ingredient in a Solid Drug Formulation

Abstract

This short communication is intended to demonstrate the influence of spectral resolution on the quantitative determination of an active ingredient in a solid drug formulation by diffuse reflection near infrared spectroscopy. As model system we have chosen a mixture of the active ingredient acetylsalicylic acid (aspirin) with cellulose and starch as excipients.

Keywords

solid drug formulation spectral resolution near infrared spectroscopy

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