The Availability of Trace Elements in Intravenous Hyperalimentation Solutions

Abstract

A study of the level and availability of trace elements in commercial and compounded hyperalimentation solutions was performed. Analyses of the zinc, copper, and manganese content of Aminosol^®, Amigen^®, Cutter Protein Hydrolysate^®, and FreAmine II^® were carried out using atomic absorption spectrophotometry. Zinc was found to be present in the highest concentrations in the solutions and copper in the lowest. Although the concentrations of a particular element varied between batches of a given solution, there was a greater variation in concentrations between the different nitrogen sources. No loss of trace elements by precipitation or absorption occurred following their addition to a compounded hyperalimentation solution. A suggested trace element solution for supplementation to a compounded TPN preparation is presented.

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