Fourier transform (FT) Raman studies of 40 tissue samples from the human stomach, including 22 normal and 18 malignant tissue samples, were performed. These stomach tissue samples had been classified as normal or malignant on the basis of pathological studies and biopsy detection. The results indicate that a series of major bands in the FT-Raman spectrum can be used to distinguish the malignant tissue from the normal tissue. Subtraction spectra support the result of the spectroscopic identification. Statistical analysis is also in agreement with the FT-Raman measurements.
Lin-VienD.ColthupN. B.FateleyW. G.GrasselliJ. G., The Handbook of Infrared and Raman Characteristic Frequencies of Organic Molcules (Academic Press, San Diego, 1991).
2.
GuanY.LewisE. N.LevinI. W., “Biomedical Application of Raman Spectroscopy: Tissue Differentiation and Potential Clinical Usage”, in Analytical Application of Raman Spectroscopy, PelletierM. J. Ed. (Oxford University Press, New York, 1999), Chap. 7.
WuJ.-G.XuY.-Z.XuD.-F.WuQ.-G.SunC.-W.SunK.-H.WengS.-F.ZhouJ.-M.XuG.-X., “FT-IR and FT-Raman Studies on the Oral Tissues”, in Abstracts Book Pittsburgh Conf. Anal. Chem. Appl. Spectrosc. (Orlando, FL, 1999), paper 796.
LingX.-F.SongY.-Y.LiW.-H.XuY.-Z.YangL.-M.WengS.-F.FerraroJ. R.ZhouX.-S.XuZ.SolowayR. D.WuJ.-G., “FT-Raman Spectroscopy Characterization of Stomach Tissues”, in Proceedings of the XVIIth International Conference on Raman Spectroscopy, ZhangS.-L. Ed. (Peking University, Beijing, China, 2000), p. 786.
7.
DasariR. R.FeldM. S., “Light Scattering and Raman Spectroscopy for Biomedical Analysis and Disease Diagnosis”, in Proceeding of the XVIIth International Conference on Raman Spectroscopy, ZhangS.-L. Ed. (Peking University, Beijing, China, 2000), p. 1044.
LingX.-F.LiW.-H.XuY.-Z.ZhangT.-L.WengS.-F.FateleyW. G.ZhouX.-S.WuJ.-G., “FT-MIR Fiber Optics Study on Malignant and Normal Tissues of Colon”, in Abstracts Book, Pittsburgh Conf. Anal. Chem. Appl. Spectrosc. (New Orleans, LA, 2000), paper 1307.
10.
WengS.-F.LingX.-F.SongY.-Y.XuY.-Z.LiW.-H.Xu ZhangYangL.-M.SunW.-X.ZhouX.-S.WuJ.-G., American Clinical Laboratory19, 20 (2000).