A 60-year-old man developed a bullous contact dermatitis after topical corticosteroid treatment of dermatitis on his lower leg. Subsequent patch testing showed cross-reactions to numerous group B and group D corticosteroids as well as cross-reactions to group C desoximetasone and group D1 mometasone furoate. His patch-test result was negative for the group A corticosteroids hydrocortisone and tixocortol pivalate. We discuss the uncommon finding of cross-reactions to desoximetasone and mometasone furoate.
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References
1.
CoopmanS, DegreefH, Dooms-GoossensA. Identification of cross-reaction patterns in allergic contact dermatitis from topical corticosteroids. Br J Dermatol, 1989; 121:27-43.
2.
LepoittevinJP, DriegheJ, Dooms-GoossensA. Studies in patients with corticosteroid contact allergy: understanding cross-reactivity among different steroids. Arch Dermatol, 1995; 131:31-7.
3.
WilkinsonSM, HollisS, BeckHM. Reactions to other corticosteroids in patients with allergic contact dermatitis from hydrocortisone. Br J Dermatol, 1995; 132:766-71.
4.
GuinJD. Contact hypersensitivity to topical corticosteroids. J Am Acad Dermatol, 1984; 10:773-82.
MaturaM, GoossensA. Contact allergy to corticosteroids. Allergy, 2000; 55:698-704.
7.
WilkinsonSM, JonesMF. Corticosteroid usage and binding to arginine: determinants of corticosteroid hypersensitivity. Br J Dermatol, 1996; 135:225-30.
8.
LauermaA. Screening for corticosteroid contact sensitivity. Contact Dermatitis, 1991; 24:123-30.
9.
RietschelRL, FowlerJF. The role of patch testing. In: RietschelRL, FowlerJF, editors. Fisher's contact dermatitis. 4th ed. Baltimore: Williams & Wilkins;. 1995. p. 29.
10.
BircherA, ThurlimannW, HunzikerT, et al.Contact hypersensitivity to corticosteroids in routine patch test patients. Dermatology, 1995; 191:109-14.
DunkelFG, ElsnerP, BurgG. Contact allergies to topical corticosteroids: 10 cases of contact dermatitis. Contact Dermatitis, 1991; 25: 97-103.
14.
BircherAJ, LevyF, LangauerS, LepoittevinJP. Contact allergy to topical corticosteroids and systemic contact dermatitis from prednisolone with tolerance of triamcinolone. Arch Derm Venereol, 1995; 75:490-3.
15.
VenningVA. Fluticasone propionate sensitivity in a patient with contact allergy to multiple corticosteroids. Contact Dermatitis, 1995; 33:48-71.
16.
ChewAL, MaibachHI. Multiple corticosteroid orally elicited allergic contact dermatitis in a patient with multiple topical corticosteroid allergic contact dermatitis. Cutis, 2000; 65:307-11.
17.
Dooms-GoossensAE, DegreefHJ, MarienKJ, CoopmanSA. Contact allergy to corticosteroids: a frequently missed diagnosis?. J Am Acad Dermatol, 1989; 21:538-43.
18.
BrambillaL, BoneschiV, ChiappinoG, et al.Allergic reactions to topical desoxymethasone and oral triamcinolone. Contact Dermatitis, 1989; 21:272-3.
19.
WilkinsonSM, CartwrightPH, EnglishUSC. Hydrocortisone: an important cutaneous allergen. Lancet, 1991; 337:761-2.
20.
WilkinsonSM. Corticosteroid cross-reactions: an alternative view. Contact Dermatitis, 2000; 42:59-63.
21.
Dooms-GoossensA, MorrenM. Results of routine patch testing with corticosteroid series in 2073 patients. Contact Dermatitis, 1992; 26:82-9.
22.
BelsitoDV. Allergic contact dermatitis to topical glucocorticoids. Cutis, 1993; 52:291-4.
23.
RaasanenL, TuomiML. Cross-sensitization to mometasone furoate in patients with corticosteroid contact allergy. Contact Dermatitis, 1992; 27:323-5.
24.
KilpioK, HannukselaM. Corticosteroid allergy in asthma. Allergy, 2003; 58:1131-5.
