Hepatitis B Virus and Hepatitis C Virus Seroprevalence in the Elderly Living in Nursing Homes

Abstract

Background

Communal living situations such as nursing homes create a risk for the spread of hepatitis B virus and hepatitis C virus (HCV). The aim of this study was to determine the seroprevalence of hepatitis B virus and HCV in the elderly living in 2 nursing homes in Ankara, Turkey.

Methods

A total of 227 persons (mean age, 76.11 ± 8.55 years) participated in this cross-sectional study. All individuals were investigated seroprevalence for hepatitis B surface antigen (HB_sAg), anti-HBs immunoglobulin G (IgG), anti-hepatitis B core IgG, and anti-HCV IgG.

Results

Positive seroprevalence was 11.9% for HB_sAg, 48.0% for anti-HBs IgG, 25.1% for anti-hepatitis B core IgG, and 2.5% for anti-HCV IgG. Hepatitis B surface antigen positivity was 12.4% in males and 11.5% in females (P > 0.05); and the seroprevalence was 10.4% for those living in nursing homes for 1 year or less and 13.0% for those living in nursing homes for more than 1 year (P > 0.05).

Conclusions

The fact that nearly half of those living in nursing homes had not encountered hepatitis B infection or had not received hepatitis B vaccination indicates the need for administering hepatitis B vaccines in this group.

Keywords

hepatitis B virus hepatitis C virus elderly vaccination

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References

Mistik

, Balik

. Epidemiological analysis of viral hepatitis in Turkey. In: Tekeli

, Balik

, Eds. Viral Hepatitis. Istanbul, Turkey:

The Association of Struggle Viral Hepatitis;

2003:10–55 (in Turkish).

Tanaka

, Kumagai

, Katayama

, . Sex- and age-specific carriers of hepatitis B and C viruses in Japan estimated by the prevalence in the 3,485,648 first-time blood donors during 1995-2000. Intervirology. 2004;47:32–40.

Margolin

. Viral Hepatitis. In: Wallace

, Doebbeling

, Eds. Maxcy-Rosenau-Last, Public Health and Preventive Medicine. 2nd ed. USA: Appleton-Lange Press; 1998:174–175.

The Ministry of Health of Turkey. News and Announcements. Available at http://www.saglik.gov.tr/TR/istatistik/2006/tablo23.htm, Accessed November 2007.

Ergin

. Hepatitis B. In: Aktas

, Hizel

, Eds. Immunization in Adults. Ankara, Turkey: Gazi University, Medical Faculty, Publising of 20th anniversary; No: 6) 1999:37–51 (in Turkish).

Ertan

, Eker

, Gungen

. The standardized mini mental state examination for illiterate Turkish elderly population. 2nd International Symposium on Neurophysiologic and Neuropsychological Assessment of Mental and Behavioral Disorders. Bursa, Turkey. Abstract 1999, no: 13.

Sugauchi

, Mizokami

, Orito

, . Hepatitis B virus infection among residents of a nursing home for the elderly: seroepidemiological study and molecular evolutionary analysis. J Med Virol. 2000;62:456–4628.

Oncu

, Oncu

, Sakarya

. Hepatitis A and B seropositivity among medical students. Health Policy. 2005;74:39–45.

Altindis

, Yilmaz

, Dikengil

, . Seroprevalence and genotyping of hepatitis B, hepatitis C and HIV among healthy population and Turkish soldiers in Northern Cyprus. World J Gastroenterol. 2006;12:6792–6796.

10.

Akcam

, Uskun

, Avsar

, . Hepatitis B virus and hepatitis C virus seroprevalence in rural areas of the southwestern region of Turkey. Int J Infect Dis. 2008;13:274–284.

11.

Emekdas

, Cavuslu

, Oncul

, . Trends in hepatitis B and hepatitis C virus among blood donors over 16 years n Turkey. Eur J Epidemiol. 2006;21:299–305.

12.

Dursun

, Ertem

, Yilmaz

, . Prevalence of hepatitis B infection in the southeastern region of Turkey: comparison of risk factors for HBV infection in rural and urban areas. Jpn J Infect Dis. 2005;58:15–19.

13.

Tansug

, Duzgunsivaci

, Unal

, . Seroepidemiological study of hepatitis B virus infection. J Viral Hepat. 1999;2:96–109 (in Turkish).

14.

Altindis

. Investigation of hepatitis B and hepatitis C seroprevalence in elderly population of Afyon region in Turkey. Med J Kocatepe. 2001;2:263–267 (in Turkish).

15.

Hsu

, Chan

, Tam

, . The liver biochemical tests and serological markers of hepatitis B virus in the very old-aged population in Taiwan. Zhonghua Yi Xue Za Zhi (Taipei). 1996;57:16–21.

16.

Wang

, Chan

, Chou

. Differing characteristics of hepatitis B and C risk factors among elders in a rural area in Taiwan. J Gerontol A Biol Sci Med Sci. 1998;53:M107–111.

17.

Chien

, Dundoo

, Horani

, . Seroprevalence of viral hepatitis in an older nursing home population. J Am Geriatr Soc. 1999;47:1110–1113.

18.

Dreesman

, Baillot

, Hamschmidt

, . Outbreak of hepatitis B in a nursing home associated with capillary blood sampling. Epidemiol Infect. 2006;134:1102–1113.

19.

The Ministry of Health of Turkey. News and Announcements. Available at http://www.saglik.gov.tr/TR/BelgeGoster.aspx?F6E10F8892433CFF71BE64510F6C8BC9531B8E8429B26AF0. Accessed November 2007.

20.

Basaras

, Santamaria

, Sarsa

, . Seroprevalence of hepatitis B and C, and human immunodeficiency type 1 viruses in a rural population from the Republic of Equatorial Guinea. Trans R Soc Trop Med Hyg. 1999;93:250–252.