Heat Shock Protein 70 Gene Polymorphisms in Japanese Patients with Aspirin-Exacerbated Respiratory Disease

Kiang JG , Tsokos GC. Heat shock protein 70 kDa: molecular biology, biochemistry, and physiology. Pharmacol Ther. 1998; 80: 183–201.

Sistonen L , Sarge KD , Morimoto RI. Human heat shock factors 1 and 2 are differentially activated and can synergistically induce hsp70 gene transcription. Mol Cell Biol. 1994; 14: 2087–2099.

Martins GA , David CM , Mitchell C , . Expression of heat shock protein 70 in leukocytes of patients with sepsis. Int J Mol Med. 1999; 3: 401–404.

Milner CM , Campbell RD. Structure and expression of the three MHC-linked HSP70 genes. Immunogenetics. 1990; 32: 242–251.

Hunat C , Morimoto RI. Conserved features of eukaryotic hsp70 genes revealed by comparison with the nucleotide sequence of human hsp70. Proc Natl Acad Sci U S A. 1985; 82: 6455–6459.

Ito Y , Ando A , Ando H , . Genomic structure of the spermatid-specific hsp70 homologue gene located in the class III region of the major histocompatibility complex of mouse and man. J Biochem (Tokyo). 1998; 124: 347–353.

Waterer GW , Elbaahlawan L , Quansney MW , . Heat shock protein 70-2+1267 AA homozygotes have an increased risk of septic shock protein in adults with community-acquired pneumonia. Crit Care Med. 2003; 31: 1367–1372.

Temple SEL , Cheong KY , Ardlie KG , . The septic shock associated HSPA1B1267 polymorphism influences production of HSPA1A and HSPA1B. Intensive Care Med. 2004; 30: 1761–1767.

Kee C , Cheong KY , Pham K , . Genetic variation in heat shock protein 70 is associated with septic shock: narrowing the association to a specific haplotype. Int J Immunogenet. 2008; 35: 465–473.

Stevenson DD , Sanchez-Borges M , Szczeklik A. Classification of allergic and pseudoallergic reactions to drugs that inhibit cyclooxygenase enzymes. Ann Allergy Asthma Immunol. 2001; 87: 177–180.

Schafer D , Maune S. Pathogenic mechanisms and in vitro diagnosis of AERD. J Allergy (Cairo). 2012; 2012: 789232.

Sanak M , Simon HU , Szczeklik A. Leukotriene C4 synthase promoter polymorphism and risk of aspirin-induced asthma. Lancet. 1997; 350: 1599–1600.

Kawagishi Y , Mita H , Taniguchi M , . Leukotriene C4 synthase promoter polymorphism in Japanese patients with aspirin-induced asthma. J Allergy Clin Immunol. 2002; 109: 936–942.

Kim SH , Bae JS , Suh CH , . Polymorphism of tandem repeat in promoter of 5-lipoxygenase in ASA-intolerant asthma: a positive association with airway hyperresponsiveness. Allergy. 2005; 60: 760–765.

Kim SH , Oh JM , Kim YS , . Cysteinyl leukotriene receptor 1 promoter polymorphism is associated with aspirin-intolerant asthma in males. Clin Exp Allergy. 2006; 36: 433–439.

Van Sambeek R , Stevenson DD , Baldasaro M , . 5′ Flanking region polymorphism of the gene encoding leukotriene C4 synthase does not correlate with aspirin-intolerant asthma phenotype in the United States. J Allergy Clin Immunol. 2000; 106: 72–76.

Choi JH , Park HS , Oh HB , . Leukotriene-related gene polymorphisms in ASA-intolerant asthma: an association with haplotype of 5-lipoxygenase. Hum Genet. 2004; 114: 337–344.

Higashi N , Mita H , Ono E , . Profile of eicosanoid generation in aspirin-intolerant asthma and anaphylaxis assessed by new biomarkers. J Allergy Clin Immunol. 2010; 125: 1084–1091.

May A , Weber A , Gall H , . Means of increasing sensitivity of an in vitro diagnostic test for aspirin intolerance. Clin Exp Allergy. 1999; 29: 1402–1411.

Schafer D , Schmid M , Gode UC , . Dynamics of eicosanoids in peripheral blood cells during bronchial provocation in aspirin-intolerant asthmatics. Eur Respir J. 1999; 13: 638–646.

de Weck AL , Sanz ML. Celluler allergen stimulation test (CAST) 2003, a review. J Investig Allergol Clin Immunol. 2004; 14: 253–273.

Sanz ML , Gamboa P , de Weck AL. A new combined test with flowcytometric basophil activation and determination of sulfidoleukotrienes is useful for in vitro diagnosis of hypersensitivity to aspirin and other nonsteroidal anti-inflammatory drugs. Int Arch Allergy Immunol. 2005; 136: 58–72.

Gray PA , Warner TD , Vojnovic I , . Effects of non-steroidal anti-inflammatory drugs on cyclooxygenase and lipoxygenase activity in whole blood from aspirin-sensitive asthmatics vs healthy donors. Br J Pharmacol. 2002; 137: 1031–1038.

Kohyama K , Abe S , Kodaira K , . Arg16Gly β2-adrenergic receptor gene polymorphism in Japanese patients with aspirin-exacerbated respiratory disease. Int Arch Allergy Immunol. 2011; 156: 405–411.

Kohyama K , Abe S , Kodaira K , . Polymorphisms of the CYP2C19 gene in Japanese patients with aspirin-exacerbated respiratory disease. J Allergy Clin Immunol. 2011; 128: 1117–1120.

Kohyama K , Abe S , Kodaira K , . IL-13 and IL-17A gene polymorphisms in Japanese patients with aspirin-exacerbated respiratory disease. Ann Allergy Asthma Immunol. 2011; 107: 510–516.

Kohyama K , Hashimoto M , Abe S , . Thromboxane A₂ receptor +795T>C and chemoattractant receptor-homologous molecule expressed on Th₂ cells −466T>C gene polymorphisms in patients with aspirin-exacerbated respiratory disease. Mol Med Report. 2012; 5: 477–482.

Vignola AM , Chanez P , Polla BS , . Increased expression of heat shock protein 70 on airway cells in asthma and chronic bronchitis. Am J Respir Cell Mol Biol. 1995; 13: 683–691.

Bertorelli G , Bocchino V , Xiasong Z , . Heat-shock protein 70 upregulation is related to HLA-DR expression in bronchial asthma. Effects of inhaled glucocorticoids. Clin Exp Allergy. 1998; 28: 551–560.

Polla BS , Bachelet M , Dall'Ava J , . Heat-shock proteins in inflammation and asthma: Dr Jekyll or Mr Hyde? Clin Exp Allergy. 1998; 28: 527–529.

Aron Y , Busson M , Polla BS , . Analysis of hsp70 gene polymorphism in allergic asthma. Allergy. 1999; 54: 165–170.

Paganelli R , Ansotegui IJ , Sastre J , . Specific IgE antibodies in the diagnosis of atopic disease. Allergy. 1998; 53: 763–768.

Linden CC , Misiak RT , Wegienka G , . Analysis of allergen specific IgE cut points to cat and dog in the Childhood Allergy Study. Ann Allergy Asthma Immunol. 2011; 106: 153–158.

Li SS , Khalid N , Carlson C , . Estimating haplotype frequencies and standard errors for multiple single nucleotide polymorphisms. Biostatistics. 2003; 4: 513–522.

Zao LP , Li SS , Khalid N. A method for the assessment of disease associations with single-nucleotide polymorphism haplotypes and environmental variables in case-control studies. Am J Hum Genet. 2003; 72: 1231–1250.

Smith RS , Meyers DA , Peters SP , . Sequence analysis of HSPA1A and HSPA1B in a multi-ethnic study population. DNA Seq. 2007; 18: 47–53.

Milner CM , Campbell RD. Polymorphic analysis of the three MHC-linked HSP70 genes. Immunogenetics. 1992; 36: 357–362.

Sampson AP , Cowburn AS , Sladek K , . Profound overexpression of leukotriene C4 synthase in bronchial biopsies from aspirin-intolerant asthmatic patients. Int Arch Allergy Immunol. 1997; 113: 355–357.

Szczeklik A , Nizankowska E , Duplaga M. Natural history of aspirin-induced asthma. AIANE Investigators. European network on aspirin-induced asthma. Eur Respir J. 2000; 16: 432–436.

Aberer W , Bircher A , Romano A , . Drug provocation testing in the diagnosis of drug hypersensitivity reactions: general considerations. Allergy. 2003; 58: 854–863.

Buhl T , Meynberg HC , Kaune KM , . Long-term follow-up of patients with hypersensitivity to nonsteroidal anti-inflammatory drugs reveals shortcomings in compliance and care. J Allergy Clin Immunol. 2011; 127: 284–285.

Fawcett TW , Xu Q , Holbrook NJ. Potentiation of heat stress-induced hsp70 expression in vivo by aspirin. Cell Stress Chaperones. 1997; 2: 104–109.

Amici C , Rossi A , Santoto MG. Aspirin enhances thermotolerance in human erythroleukemic cells: an effect associated with the modulation of the heat shock response. Cancer Res. 1995; 55: 4452–4457.

Gehrmann M , Brunner M , Pfister K , . Differential up-regulation of cytosolic and membrane-bound heat shock protein 70 in tumor cells by anti-inflammatory drugs. Clin Cancer Res. 2004; 10: 3354–3364.

Mortaz E , Redegeld FA , Bloksma N , . Induction of HSP70 is dispensable for anti-inflammatory action of heat shock or NSAIDs in mast cells. Exp Hematol. 2006; 34: 414–423.

Mortaz E , Redegeld FA , Nijkamp FP , . Acetylsalicylic acid–induced release of HSP70 from mast cells results in cell activation through TLR pathway. Exp Hematol. 2006; 34: 8–18.

Reuter S , Heinz A , Sieren M , . Mast cell-derived tumor necrosis factor is essential for allergic airway disease. Eur Respir J. 2008; 31: 773–782.

Oettgen HC. Mast cells and tumor necrosis factor alpha (TNF-α) partners in crime in asthma pathogenesis. Clin Immunol. 2011; 140: 1–2.

Lukacs NW , Strieter RM , Chensue SW , . TNF-alpha mediates recruitment of neutrophils and eosinophils during airway inflammation. J Immunol. 1995; 154: 5411–5417.

Maillet I , Schnyder-Candrian S , Couillin I , . Allergic lung inflammation is mediated by soluble tumor necrosis factor (TNF) and attenuated by dominant-negative TNF biologics. Am Respir Cell Mol Biol. 2011; 45: 731–739.

Adamjee J , Suh YJ , Park HS , . Expression of 5-lipoxygenase and cyclooxygenase pathway enzymes in nasal polyps of patients with aspirin-intolerant asthma. J Pathol. 2006; 209: 392–399.

O'Sullivan S , Dahlen B , Roquet A , . Urinary 9 alpha, 11 beta-PGF2 as a marker of mast cell activation in allergic and aspirin-intolerant asthma. Adv Exp Med Biol. 1997; 433: 159–162.

O'Sullivan S , Dahlen B , Dahlen SE , . Increased urinary excretion of the prostaglandin D2 metabolite 9 alpha, 11 beta-prostaglandin F2 after aspirin challenge supports mast cell activation in aspirin-induced airway obstruction. J Allergy Clin Immunol. 1996; 98: 421–432.

Mortaz E , Engels F , Nijikamp FP , . New insights on the possible role of mast cells in aspirin-induced asthma. Curr Mol Pharmacol. 2009; 2: 182–189.

Zander KA , Saavedra MT , West J , . Protein microarray analysis of nasal polyps from aspirin-sensitive and aspirin-tolerant patients with chronic rhinosinusitis. Am J Rhinol Allergy. 2009; 23: 268–272.