Abstract
Summary
A precipitation reaction between extracts of Group A, Type 15 streptococci and human serum has been described. The streptococcal factor bears some similarity to the M protein, but is almost certainly a separate substance, probably protein in nature. Like the M, T and R antigens it is present on the surface of the streptococcal cell. The reactive factor has been differentiated from T and R antigens. It is not yet known whether or not the bacterial factor is antigenic, nor is it known yet whether the reaction between this factor and human serum is of other than a happenstance nature.
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