Assessment of Antral Protective Mechanisms and Intestinal Susceptibility Gradient to Ulcer Formation

Summary and conclusions

1) In Group II type of preparation described herein (antral exclusion with 50% of acid peptic secreting tissue attached to antrum) no abettment of ulcer diathesis was noted. Ulcer was not observed at either neostoma. 2) When, however, a similar fundic pouch was attached to the duodenum (Group I preparation) ulcer occurred at this neostoma in 50% of dogs studied and interestingly not in the short duodenal segment, but just over on the jejunal side, an occurrence which suggests an increased gradient of susceptibility to peptic ulceration.