Abstract
Summary
The effect of acute starvation and dehydration in rats, on “takes” of Walker 256 cells following their injection subcutaneously has been investigated. Our results indicate that starvation and dehydration for 48 hours do not increase susceptibility of the rat to subcutaneous inoculation of Walker tumor, but if starvation is continued for 7 days there is increase in percentage “takes” of the tumor as compared to incidence in normal healthy animals. There is also an increase in “takes” of implanted tumor in young rats 28 days of age compared to more mature rats.
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