Some Factors which Influence the Catalytic Activity of Pancreatic Cholesterol Esterase

Summary

These data indicate that pancreatic cholesterol esterase catalyzes both synthesis and hydrolysis of cholesteryl oleate at a single pH, but the reaction which predominates in presence of both substrates is governed by the electrolyte concentration. Rate of synthesis of 4C¹⁴-cholesteryl oleate is decreased in proportion to relative concentration of β-sitosterol.

The authors acknowledge with gratitude the continued interest of Drs. R. E. Shipley and C. W. Pettinga.