Abstract
Summary
The effect of D2O on growth of 3 stable mammalian cell lines (HeLa, L and L-5178Y) has been investigated. As D2O concentration was increased all cells showed increased water content and dry weight and a slower growth rate. Cytological investigations showed an increase in number of multinucleated cells and a moderate increase in sudanophilic material. No significant changes in nucleic acid content were demonstrable with the staining technics used.
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