Abstract
Summary
Rabbit antisera prepared against rat Murphy-Sturm lymphosarcoma (ascites form) and normal rat lymph node exhibit extensive cross reactions with these tissues. However, antibodies in the antisera were separated into fractions of different specificities: some directed against certain characteristic antigen(s) in the tumor or in the lymph node sediment and others against the common (cross-reacting) components in both. This was done by successive adsorptions of the antisera with the tumor and lymph node sediments and elution of adsorbed antibodies from these sediments. I131 labeled antibody was used for the studies.
We wish to thank Miss Pat Gorman and Mr. Norman Misso for technical assistance and Mr. Jacob Planinsek for the rat tissue used.
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