Abstract
Summary
A relative increase in non-infective or incomplete vaccinia virus occurs during virus growth in the chorioallantoic membrane of 12-day-old eggs incubated at 26°C and 30°C. Vaccinia growth in membranes of eggs 8 and 15 days of age is reduced but no increase in non-infective vaccinia was found. Serial passage of high concentrations of vaccinia virus in 12-day-old eggs likewise failed to increase the proportion of non-infective virus.
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