Human Adenovirus Complement-Fixing Antibodies in New York Family Dogs

Summary

A survey of New York dog serums for adenovirus CF antibodies showed an incidence of 2.2%. Such a low incidence suggests that dogs are only incidental hosts for agents that evoke antibodies which fix complement with human adenovirus CF antigens. Infections of dogs by non-primate adeno-viruses could not be excluded since these may also evoke antibodies which fix complement with human type adenovirus antigens. A previous suggestion that alien adenovirus infections in dogs might partially account for the varied clinical and serological responses seen when dogs are infected with ICH virus now appears unlikely.