Abstract
Summary
Results are presented showing that it is possible to restore neuromuscular transmission in botulinum paralyzed rat skeletal muscle by inducing the formation of new motor nerve terminals. The toxin, bound to the original endings, does not interfere with the regeneration following a crush of the motor nerve, and the new terminals can establish effective neuromuscular transmission after a few days. In muscles treated with the toxin alone the paralysis lasts for several weeks.
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