Massive Diuresis Following Renal Homotransplantation. ∗

Summary

Characterization of the diuresis experienced by a 19-year-old recipient of a renal homotransplant revealed certain features in common with the diuresis seen in experimental osmotic diuresis in normal subjects, and with the diuresis seen following relief of urinary tract obstruction and in other salt-wasting syndromes. The preponderant unreabsorbed solutes were sodium and chloride rather than urea. Since the salt wasting state did not persist, it may have been due to volume expansion and to an enhanced filtration rate, rather than to a tubular reabsorptive defect.