The effect of lead on the germ cells of the male rabbit and fowl as indicated by their progeny. 1

The experiments of Stockard 2 on guinea pigs and of Cole and Davis 3 on rabbits have shown conclusively that alcohol has a deleterious effect on the germ cells of the male. In the experiments here reported lead, in the form of lead acetate, was substituted for the alcohol, lead being chosen because of its reputed effect upon the offspring of workers, whether male or female, in trades where they are exposed to lead in its various forms. The method of double mating described by Cole and Davis was employed. This consists in breeding a female of a certain type to two males at the same period. The males are of such gametic constitution that the young of each may be identified by color or other characteristics. The experimental animals used were rabbits and fowls. The lead acetate was mixed with sugar of milk and fed in gelatin capsules.