Renal Arteriovenous Reduction in Hemoglobin Concentration in the Anesthetized Dog. ∗

Summary

A renal arteriovenous reduction in hemoglobin concentration measured as carbon hemoglobin or acid hematin was observed in the dog. It largely disappeared when care was taken to avoid producing changes in the animal by the sampling procedure. When such care was taken, however, a renal arteriovenous reduction in hemoglobin concentration measured as cyanmethemoglobin was still found. It would seem that this reduction was at least in part due to a process intrinsic to the kidney and that it must have involved the measurement of an unidentified substance or possibly a modification of the hemoglobin molecule by the method for determining hemoglobin as cyanmethemoglobin to a different degree than by the other methods.