Abstract
Summary
Acetylcholinesterase activity, essentially similar in fetal, newborn and adult sheep erythrocytes, was only 25% that of cells from adult humans. Erythrocyte glucose-6-phosphate dehydrogenase activity was 3 times higher in fetuses and newborn lambs than in adult sheep. Cells from adult animals had only 1/5 the activity seen in erythrocytes from normal adult humans. When sheep erythrocytes were separated into light and heavy cell fractions, the activities of both enzymes were increased in the lighter fraction with higher reticulocyte content and decreased in the fraction containing the older cells.
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