Response of Thymus and other Human Lymphoid Tissues to PHA,PWM and Genetically Dissimilar Lymphoid Cells. ∗

Summary

When human thymus, tonsil and appendix cells were exposed in vitro to PHA, PWM or allogeneic lymphoid cells for 2 to 3 days, blast cells were observed. Studies suggest that in mixed lymphoid cultures, the blast cells may have originated from both donors. Infrequently, in cultures containing transformed cells, an absence of H³-thymidine incorporation was observed by radioautography.