Abstract
Summary
Anaphylactic release of histamine was induced in mouse mast cells after sensitization with mouse, rat, or rabbit antibodies. As compared with homologous antibodies, rat antibodies were quite effective, whereas, rabbit antibodies were poorly effective. Guinea pig antibodies (γG1 and γG2) were ineffective. Pepsin-digested preparations of rabbit antibodies were unable to sensitize mouse mast cells, or mouse skin, for the PCA reaction.
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