Abstract
Summary
The glycoprotein found in human placental fluids that inhibits the hemagglutination of H-1 and HB viruses has been obtained in a high degree of purity as shown by disc electrophoresis and immunodiffusion. It sediments as a macroglobulin whose biological activity can be destroyed by treatment with trypsin, chymotrypsin, papain, neuraminidase, or sodium metaperiodate. The inhibitor possesses a remarkable capacity for reacting with H-1 virus since it is active in as low a concentration as 0.004 μg/ml.
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