Abstract
Summary
Starch block electrophoresis of rat serum resulted in five glutamic-oxalacetic transaminase (GOT) isoenzyme fractions. Carbon tetrachloride-induced liver injury was associated with marked rise of all five fractions but to a different degree. The cationic A2 fraction increase was greater. This altered isoenzyme distribution resembled the pattern of GOT isoenzymes in the liver homogenate. The implication of these findings with respect to the transfer of the intracellular hepatic GOT into the serum is considered.
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