Abstract
Summary
Two groups of rats were fed respectively a magnesium-deficient and a magnesium-supplemented diet. No alteration in activity of lactate dehydrogenase in glomeruli and proximal tubules was evident in the magnesium-deficient animals after either 3 or 9 days on the diet. Activity of glucose-6-phosphate dehydrogenase increased significantly in the proximal portion of the proximal tubules after 3 days while it decreased in the distal portion of the proximal tubules after 9 days in the magnesium-deficient rats as compared to the controls. The change in activity of glucose-6-phosphate dehydrogenase in the distal portion of proximal tubules may be secondary to a redistribution of intermediary substrates into subcellular compartments.
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