Skin Composition Following Exposure of Mice to a Hyperbaric Oxygen-Nitrogen Mixture ∗

Summary

Mice were exposed to 23 cycles each consisting of compression at 45 lb/in.² in an air-oxygen mixture containing 27% oxygen for 72 hr followed by 4 days of recovery. The skin was analyzed for salt-soluble, acid-soluble and insoluble collagen, hyaluronic acid, chondroitin sulfate, and fluorogenic material. Growth was less than that of the controls. There was 25% less salt-soluble collagen and 20% more fluorogenic material but the other values did not differ significantly from that expected on the basis of size.