Aortic Cholesterol and the Plasma Lipoproteins of the Cholesterol-Fed Cockerel ∗

Summary

In an experiment with 75 cholesterol-fed cockerels, in which deposition of cholesterol in the aortic wall was correlated with the various lipoprotein lipids, it was found that no significant correlation existed with the heavy density lipoprotein fraction. Significant correlations were present with the _Sf0-12, S_f12-20 and S_f20 cholesterol after 10 weeks. In fact, the variance in aortic cholesterol could be largely explained by S_{f 20} lipoprotein cholesterol. None of the measured plasma lipid parameters correleated with aortic phospholipid or total fatty acids as well as with the aortic cholesterol.