Effects on Leucine- 3 H Incorporation by Submandibular Gland Cells of Rat Neonates ∗

Summary

Effect of anoxia on leucine-³H incorporation by submandibular gland cells of neonatal rats has been studied by means of quantitative radioautography. The results show that there is a marked suppression of leucine-³H incorporation during the first 4 hr following the anoxia administration. There is an apparent recovery by 24 hr, and no difference between the experimental and control animals is observed after this time. It is concluded that the synthesis of overall cytoplasmic proteins is temporarily impaired after a brief exposure to anoxia in submandibular gland cells of neonatal rats.