Total Acid-Labile CO 2 Content in Dog Renal Cortex and Medulla 1

Summary

Total acid-labile CO₂ was measured in aliquots of dog renal cortex and medulla frozen in liquid nitrogen. A higher (15.87 μmoles/g wet weight vs 13.55 μmoles/g wet weight, p <.05) acid-labile CO₂ content was found in the renal medulla. It is suggested that the higher medullary total acid-labile CO₂ content is primarily due to a high [HCO₃-] in the medullary intracellular fluid rather than to a high medullary Pco₂.