Reaction of Bovine Conglutinin in Human in Vitro Phagocytic Systems 1

Summary

Bovine conglutinin, a naturally occurring anti-C'3 factor, was studied in quantitative human in vitro phagocytosis systems. Striking antiopsonic effect was noted when conglutinin was added to phagocytic systems with gram-negative and gram-positive organisms dependent on heat-labile opsonic factors. In noncomplement-dependent test systems using isolated hyperimmune _γG opsonins, no blocking by conglutinin was noted.