Hemagglutination Properties of Adenovirus Types 20,25,and 28

Summary

Adenovirus types 20, 25, and 28 are presently included in Rosen's hemagglutination Group I, although they are generally considered as atypical members. Reexamination of these three types in our laboratory showed that (1) hemagglutination titers were consistently higher with rat than with rhesus or vervet erythrocytes, (2) hemagglutination-inhibition titers may be readily demonstrated with rat but not with rhesus erythrocytes, and (3) antigenic relationships occur with members of Group II and not with members of other groups. On the basis of these findings we propose that adenovirus types 20, 25, and 28 be classified as members of Group II rather than atypical members of Group I.