Myocardial Hypertrophy Resulting from Low Dosage Isoproterenol Administration in Rats 1

Summary

Isoproterenol, in lower doses than previously reported, was administered to rats for 13 and 31 days. This dose of isoproterenol (0.02 mg/kg once daily) was sufficient to cause a brief tachycardia and yielded significant myocardial weight gain.