Ultra-Rapid Nitrogen Balances in Man 1

Summary

Fasting healthy participants were in negative nitrogen balance when given glucose calories alone intravenously. Reversal of nitrogen balance from negative to positive occurred during the intravenous administration of an amino acid-glucose mixture. During alternating infusions of glucose and amino acid-glucose mixtures to fasting healthy participants, the pattern of negative nitrogen balance during glucose infusions alone and positive nitrogen balance during amino acid-glucose infusions remained evident as infusion periods varied from 8 to 4 to 2 to 1 hr.