Abstract
Summary
Extracts of Burkitt's lymphoma cell cultures which had been previously shown to contain an inhibitor of herpes simplex virus in vitro were used to treat rabbits with ocular herpes infection. Topical instillation of the extract into the eyes of the rabbits cured or suppressed the progression of herpetic keratitis. Histopathologic studies of the eyes of treated and control animals confirmed the inhibition of keratitis and other evidence of herpes-related ocular inflammation.
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