Abstract
Summary
Marmosets inoculated with blood specimens from human cases of hepatitis A but not from cases of hepatitis B developed hepatitis with elevation in serum enzymes and characteristic histopathologic changes. The marmoset was highly reliable for detecting, propagating and studying human hepatitis A with minimal spurious results.
The authors are grateful to Dr. W. J. McAleer and his staff for devising and performing enzyme assays, to F. Banker for capable handling of marmoset bleeding and inoculations, to P. Giesa, B. Keech, L. Hoover, W. Pouch, and F. Roach for technical assistance and to Dr. P. Conti for maintenance of the health of the animals. The pathologic examinations were made by Drs. A. Phelps, G. E. Dagle, and J. H. Vickers.
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