Abstract
Summary
Theophylline, glucagon, and SQ-20009 induce a choleresis in the dog characterized by a proportionate increase in erythritol clearance and bile flow, no increase in bile salt excretion, and by an isosmotic solution of similar electrolyte composition. The increment in bile appears to originate at the canaliculus in response to increased cyclic-AMP.
The authors are indebted to Ruthie Pettigrew and Mark Hardt for valuable technical assistance and to Dorothy Bass for preparation of the manuscript.
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